Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.66 |
| ▸ | HPGD | P15428 | 4/20 | 0.66 |
| ▸ | HTT | P42858 | 3/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.66 |
| ▸ | THRB | P10828 | 1/20 | 0.66 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 13/20 | 0.62 |
| ▸ | NPC1 | O15118 | 10/20 | 0.62 |
| ▸ | POLB | P06746 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | PKM | P14618 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 5/20 | 0.57 |
| ▸ | TSHR | P16473 | 4/20 | 0.57 |
| ▸ | TP53 | P04637 | 4/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.56 |
| ▸ | RELA | Q04206 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29803858 | 1.00 | MAPT (0.66) | MAPTALDH1A1HPGDHTTTDP1 | |
| SCHEMBL24669338 | 0.76 | MAOB (0.70) | MAPTHTTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL29803408 | 0.76 | MAOB (0.70) | MAPTHTTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL8859862 | 0.76 | KIF11 (0.61) | MAPTALDH1A1RAB9ANPC1MEN1 | |
| SCHEMBL7718014 | 0.75 | RAB9A (0.70) | MAPTALDH1A1HPGDTDP1GRM4 | |
| SCHEMBL22804219 | 0.75 | RAB9A (0.70) | MAPTALDH1A1HPGDTDP1GRM4 | |
| SCHEMBL4020988 | 0.75 | RAB9A (0.70) | MAPTALDH1A1HPGDHTTTDP1 | |
| SCHEMBL18180861 | 0.75 | RAB9A (0.70) | MAPTALDH1A1HPGDHTTTDP1 | |
| SCHEMBL3642839 | 0.74 | MAPT (0.88) | MAPTALDH1A1HPGDHTTTDP1 | |
| SCHEMBL7933157 | 0.74 | MAPT (0.52) | MAPTALDH1A1HPGDHTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |