Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.88 |
| ▸ | RAB9A | P51151 | 8/20 | 0.88 |
| ▸ | LMNA | P02545 | 8/20 | 0.88 |
| ▸ | MEN1 | O00255 | 6/20 | 0.88 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.88 |
| ▸ | TSHR | P16473 | 4/20 | 0.88 |
| ▸ | HPGD | P15428 | 3/20 | 0.88 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.88 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.75 |
| ▸ | NPC1 | O15118 | 6/20 | 0.72 |
| ▸ | PPARG | P37231 | 1/20 | 0.72 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.72 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.72 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.69 |
| ▸ | USP2 | O75604 | 2/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.69 |
| ▸ | POLB | P06746 | 3/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18180861 | 0.83 | RAB9A (0.70) | MAPTRAB9ALMNAMEN1KMT2A | |
| SCHEMBL7718014 | 0.83 | RAB9A (0.70) | MAPTRAB9ALMNAMEN1KMT2A | |
| SCHEMBL22804219 | 0.83 | RAB9A (0.70) | MAPTRAB9ALMNAMEN1KMT2A | |
| SCHEMBL4020988 | 0.83 | RAB9A (0.70) | MAPTRAB9ALMNAMEN1KMT2A | |
| SCHEMBL28958728 | 0.82 | RAB9A (0.63) | MAPTRAB9ALMNAMEN1KMT2A | |
| SCHEMBL31337431 | 0.81 | MAPT (0.70) | MAPTRAB9ALMNAMEN1KMT2A | |
| SCHEMBL11888590 | 0.79 | ALDH1A1 (1.00) | MAPTRAB9ALMNAMEN1KMT2A | |
| SCHEMBL2532969 | 0.79 | RAB9A (0.72) | MAPTRAB9ALMNAMEN1KMT2A | |
| SCHEMBL12136717 | 0.79 | KMT2A (1.00) | MAPTRAB9ALMNAMEN1KMT2A | |
| SCHEMBL4018260 | 0.78 | NPC1 (0.61) | MAPTRAB9ALMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025022031-A1 | NEW DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (ES) | 2025-01-30 | — | — | WO | disclosed |
| US-8518916-B2 | Heterocyclic derivatives as M-GLU5 antagonists | RECORDATI IRELAND LIMITED (IE) | 2013-08-27 | — | — | US | disclosed |
| EP-2178858-B1 | NOVEL HETEROCYCLIC COMPOUNDS AS MGLU5 ANTAGONISTS | RECORDATI IRELAND LTD (IE) | 2011-12-28 | — | — | EP | disclosed |
| CN-101821256-A | Novel heterocyclic compounds as mGlu5 antagonists | RECORDATI IRELAND LTD | 2010-09-01 | — | — | CN | disclosed |
| EP-2178858-A1 | NOVEL HETEROCYCLIC COMPOUNDS AS MGLU5 ANTAGONISTS | Recordati Ireland Limited (IE) | 2010-04-28 | — | — | EP | disclosed |
| US-20090042841-A1 | NOVEL HETEROCYCLIC DERIVATIVES AS M-GLU5 ANTAGONISTS | RECORDATI IRELAND LIMITED (IE) | 2009-02-12 | — | — | US | disclosed |
| WO-2009015897-A1 | NOVEL HETEROCYCLIC COMPOUNDS AS MGLU5 ANTAGONISTS | RECORDATI IRELAND LIMITED (IE) | 2009-02-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090042841-A1 | NOVEL HETEROCYCLIC DERIVATIVES AS M-GLU5 ANTAGONISTS | GRM5, GRIK5, GRM3 | MAPT 1249/4885RAB9A 1012/4885LMNA 3472/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.