Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT3A | P56704 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | F13A1 | P00488 | 1/20 | 0.46 |
| ▸ | TGM2 | P21980 | 1/20 | 0.46 |
| ▸ | TGM1 | P22735 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.43 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24671578 | 0.83 | WNT3A (0.47) | WNT3ASMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL24671474 | 0.81 | WNT3A (0.45) | WNT3ASMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL30385866 | 0.80 | WNT3A (0.56) | WNT3ASMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL29373833 | 0.80 | MAPT (0.55) | SMN1; SMN2MAPTMEN1KMT2ATSHR | |
| SCHEMBL2386743 | 0.80 | MAPT (0.55) | SMN1; SMN2MAPTMEN1KMT2ATSHR | |
| SCHEMBL24670245 | 0.79 | LMNA (0.50) | SMN1; SMN2MAPTMEN1KMT2ATSHR | |
| SCHEMBL29803679 | 0.79 | LMNA (0.50) | SMN1; SMN2MAPTMEN1KMT2ATSHR | |
| SCHEMBL28907538 | 0.79 | WNT3A (0.63) | WNT3ASMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL24669307 | 0.78 | LMNA (0.51) | SMN1; SMN2MAPTMEN1KMT2ATSHR | |
| SCHEMBL24670621 | 0.78 | CHRM1 (0.57) | SMN1; SMN2MAPTMEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |