Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 11/20 | 0.44 |
| ▸ | HTR6 | P50406 | 6/20 | 0.44 |
| ▸ | HTR2A | P28223 | 4/20 | 0.44 |
| ▸ | HTR7 | P34969 | 3/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | QDPR | P09417 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24669513 | 0.89 | HTR6 (0.46) | HTR2CHTR6HTR2AHTR7SIGMAR1 | |
| SCHEMBL24670316 | 0.89 | SIGMAR1 (0.42) | HTR2CHTR6HTR2AHTR7SIGMAR1 | |
| SCHEMBL25328675 | 0.82 | HTR2C (0.53) | HTR2CHTR6HTR2AHTR7SIGMAR1 | |
| SCHEMBL24670558 | 0.78 | HTR6 (0.46) | HTR2CHTR6HTR7SIGMAR1QDPR | |
| SCHEMBL24196806 | 0.78 | SIGMAR1 (0.55) | HTR2CHTR6HTR2AHTR7SIGMAR1 | |
| SCHEMBL27518176 | 0.76 | SIGMAR1 (0.44) | HTR2CHTR6HTR2AHTR7SIGMAR1 | |
| SCHEMBL5542927 | 0.75 | HTR2C (0.50) | HTR2CHTR6HTR2AHTR7SIGMAR1 | |
| SCHEMBL13999800 | 0.75 | SIGMAR1 (0.45) | HTR2CHTR6HTR2AHTR7SIGMAR1 | |
| SCHEMBL31701454 | 0.72 | CCNT1 (0.41) | HTR2CHTR6HTR2AHTR7QDPR | |
| SCHEMBL5019939 | 0.71 | QDPR (0.48) | HTR2CHTR6HTR2AHTR7QDPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |