Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 9/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.36 |
| ▸ | MTTP | P55157 | 3/20 | 0.33 |
| ▸ | QDPR | P09417 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24670897 | 0.94 | NAMPT (0.39) | NAMPTABCB1MTTPQDPRTRPV1 | |
| SCHEMBL24671257 | 0.94 | NAMPT (0.39) | NAMPTABCB1MTTPQDPRTRPV1 | |
| SCHEMBL24670803 | 0.93 | NAMPT (0.38) | NAMPTABCB1QDPR | |
| SCHEMBL24671554 | 0.92 | NAMPT (0.34) | NAMPTABCB1TRPV1NPC1 | |
| SCHEMBL24670937 | 0.92 | NAMPT (0.34) | NAMPTABCB1MTTPTRPV1NPC1 | |
| SCHEMBL24671510 | 0.92 | NAMPT (0.41) | NAMPTABCB1 | |
| SCHEMBL24670242 | 0.89 | NPC1 (0.35) | NAMPTABCB1TRPV1NPC1 | |
| SCHEMBL24670949 | 0.87 | NAMPT (0.41) | NAMPTNPC1 | |
| SCHEMBL24670952 | 0.87 | NAMPT (0.41) | NAMPTNPC1 | |
| SCHEMBL24670800 | 0.86 | NAMPT (0.39) | NAMPTABCB1QDPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |