Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 3/20 | 0.34 |
| ▸ | WDR5 | P61964 | 2/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.32 |
| ▸ | CDK9 | P50750 | 3/20 | 0.32 |
| ▸ | TNF | P01375 | 1/20 | 0.31 |
| ▸ | CPT2 | P23786 | 1/20 | 0.31 |
| ▸ | CPT1A | P50416 | 1/20 | 0.31 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24670926 | 0.93 | WDR5 (0.36) | NAMPTWDR5TRPV1NPC1CCNT1 | |
| SCHEMBL24671551 | 0.93 | WDR5 (0.36) | NAMPTWDR5TRPV1NPC1CCNT1 | |
| SCHEMBL24671259 | 0.92 | NAMPT (0.38) | NAMPTABCB1TRPV1NPC1 | |
| SCHEMBL24670937 | 0.92 | NAMPT (0.34) | NAMPTABCB1TRPV1NPC1CCNT1 | |
| SCHEMBL24670242 | 0.90 | NPC1 (0.35) | NAMPTABCB1TRPV1NPC1CCNT1 | |
| SCHEMBL24671510 | 0.89 | NAMPT (0.41) | NAMPTABCB1 | |
| SCHEMBL24670803 | 0.88 | NAMPT (0.38) | NAMPTABCB1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL24670832 | 0.88 | MAPT (0.37) | NAMPTABCB1TRPV1NPC1MAPT | |
| SCHEMBL24671182 | 0.86 | NAMPT (0.38) | NAMPTABCB1TRPV1NPC1CCNT1 | |
| SCHEMBL29803596 | 0.86 | NAMPT (0.38) | NAMPTABCB1TRPV1NPC1CCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |