Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 11/20 | 0.42 |
| ▸ | CDK9 | P50750 | 11/20 | 0.42 |
| ▸ | TMPRSS2 | O15393 | 3/20 | 0.40 |
| ▸ | KLK1 | P06870 | 1/20 | 0.38 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29802916 | 0.95 | TMPRSS2 (0.43) | CCNT1CDK9TMPRSS2KLK1KLK5 | |
| SCHEMBL24670704 | 0.89 | TMPRSS2 (0.40) | CCNT1CDK9TMPRSS2KLK1KLK5 | |
| SCHEMBL24671261 | 0.85 | QDPR (0.43) | CCNT1CDK9TMPRSS2KLK1KLK5 | |
| SCHEMBL24671177 | 0.85 | TMPRSS2 (0.51) | TMPRSS2MAPTKMT2ANPC1RAB9A | |
| SCHEMBL29803211 | 0.85 | TMPRSS2 (0.51) | TMPRSS2MAPTKMT2ANPC1RAB9A | |
| SCHEMBL29802957 | 0.84 | TMPRSS2 (0.44) | CCNT1CDK9TMPRSS2KLK1KLK5 | |
| SCHEMBL24670238 | 0.82 | TMPRSS2 (0.46) | CCNT1CDK9TMPRSS2TRPV1MAPT | |
| SCHEMBL24670929 | 0.82 | WDR5 (0.46) | CCNT1CDK9MAPT | |
| SCHEMBL24669441 | 0.80 | TMPRSS2 (0.53) | TMPRSS2MAPTKMT2ANPC1RAB9A | |
| SCHEMBL24670801 | 0.79 | TMPRSS2 (0.45) | TMPRSS2MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |