Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 4/20 | 0.36 |
| ▸ | NAMPT | P43490 | 3/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 5/20 | 0.35 |
| ▸ | CDK9 | P50750 | 5/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CPT2 | P23786 | 1/20 | 0.33 |
| ▸ | CPT1A | P50416 | 1/20 | 0.33 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24670926 | 1.00 | WDR5 (0.36) | WDR5NAMPTCCNT1CDK9TRPV1 | |
| SCHEMBL24671554 | 0.93 | NAMPT (0.34) | WDR5NAMPTCCNT1CDK9TRPV1 | |
| SCHEMBL24670897 | 0.91 | NAMPT (0.39) | NAMPTCCNT1CDK9TRPV1ALDH1A1 | |
| SCHEMBL24671257 | 0.91 | NAMPT (0.39) | NAMPTCCNT1CDK9TRPV1ALDH1A1 | |
| SCHEMBL29803596 | 0.91 | NAMPT (0.38) | NAMPTCCNT1CDK9TRPV1MAPT | |
| SCHEMBL24671182 | 0.91 | NAMPT (0.38) | NAMPTCCNT1CDK9TRPV1MAPT | |
| SCHEMBL24670703 | 0.90 | TRPV1 (0.36) | WDR5NAMPTCCNT1CDK9TRPV1 | |
| SCHEMBL24670707 | 0.90 | TRPV1 (0.36) | WDR5NAMPTCCNT1CDK9TRPV1 | |
| SCHEMBL24671542 | 0.89 | CDK9 (0.36) | NAMPTCCNT1CDK9TRPV1MAPT | |
| SCHEMBL24670237 | 0.89 | CDK9 (0.36) | NAMPTCCNT1CDK9TRPV1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |