Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | PRKCZ | Q05513 | 9/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | MPI | P34949 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | PRKCI | P41743 | 2/20 | 0.50 |
| ▸ | FHIT | P49789 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10532585 | 0.87 | ALDH1A1 (0.75) | ALDH1A1SMN1; SMN2MAPK1POLBPRKCZ | |
| SCHEMBL13369154 | 0.83 | ALDH1A1 (0.69) | ALDH1A1SMN1; SMN2MAPK1POLBPRKCZ | |
| SCHEMBL4933891 | 0.82 | ALDH1A1 (0.68) | ALDH1A1SMN1; SMN2MAPK1POLBPRKCZ | |
| SCHEMBL16663489 | 0.82 | ALDH1A1 (0.68) | ALDH1A1SMN1; SMN2MAPK1POLBPRKCZ | |
| SCHEMBL5278960 | 0.81 | GABRP (0.45) | ALDH1A1SMN1; SMN2MAPK1POLBHSD17B10 | |
| SCHEMBL9097409 | 0.81 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2MAPK1POLBPRKCZ | |
| SCHEMBL13814898 | 0.79 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2MAPK1POLBPRKCZ | |
| SCHEMBL162443 | 0.79 | ALDH1A1 (0.63) | ALDH1A1SMN1; SMN2MAPK1POLBPRKCZ | |
| SCHEMBL6031612 | 0.78 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2MAPK1POLBPRKCZ | |
| SCHEMBL8907488 | 0.78 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2MAPK1POLBPRKCZ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220356164-A1 | 2-AMINOSELENOPHEN COMPOUNDS WITH ANTI-DRUG RESISTANT BACTERIA ACTIVITY AND A METHOD OF PREPARING THE SAME | ZHUHAI JINAN SELENIUM SOURCE NANOTECHNOLOGY CO., LTD. (CN) | 2022-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220356164-A1 | 2-AMINOSELENOPHEN COMPOUNDS WITH ANTI-DRUG RESISTANT BACTERIA ACTIVITY AND A METHOD OF PREPARING THE SAME | SLC11A2, LSS, AASDHPPT | ALDH1A1 2155/4885SMN1; SMN2 4340/4885MAPK1 2588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.