Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.31 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
| ▸ | HTR1B | P28222 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14992608 | 0.86 | IMPDH2 (0.32) | ALDH1A1TSHRIMPDH2 | |
| SCHEMBL2464560 | 0.86 | CYP3A4 (0.39) | ALDH1A1TSHRIMPDH2 | |
| SCHEMBL1124861 | 0.81 | HRH3 (0.36) | ALDH1A1HTR1DHTR1B | |
| SCHEMBL3125416 | 0.77 | HTR1D (0.37) | ALDH1A1HTR1DHTR1B | |
| SCHEMBL2463078 | 0.77 | — | — | |
| SCHEMBL13263628 | 0.77 | NPSR1 (0.42) | ALDH1A1TSHRIMPDH2L3MBTL1PDE10A | |
| SCHEMBL2470125 | 0.77 | CYP3A4 (0.41) | ALDH1A1 | |
| SCHEMBL2464817 | 0.77 | P2RX7 (0.33) | ALDH1A1TSHR | |
| SCHEMBL21495042 | 0.76 | HTR1D (0.50) | ALDH1A1TSHRHTR1DHTR1B | |
| SCHEMBL14993155 | 0.74 | ALDH1A1 (0.40) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2785714-A1 | IMPROVED MODULATORS OF HEC1 ACTIVITY AND METHODS THEREFOR | Taivex Therapeutics Corporation (TW) | 2014-10-08 | — | — | EP | disclosed |
| WO-2013082324-A1 | IMPROVED MODULATORS OF HEC1 ACTIVITY AND METHODS THEREFOR | TAIVEX THERAPEUTICS CORPORATION (TW) | 2013-06-06 | — | — | WO | disclosed |
| EP-2547676-A2 | MODULATORS OF HEC1 ACTIVITY AND METHODS THEREFOR | Taivex Therapeutics Inc. (TW) | 2013-01-23 | — | — | EP | disclosed |
| WO-2011115998-A2 | MODULATORS OF HEC1 ACTIVITY AND METHODS THEREFOR | TAIVEX THERAPEUTICS INC. (CN) | 2011-09-22 | — | — | WO | disclosed |
| WO-2010001220-A1 | NEW 1,2,4-TRIAZINE DERIVATIVES AND BIOLOGICAL APPLICATIONS THEREOF | MUTABILIS SA (FR) | 2010-01-07 | — | — | WO | disclosed |