Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | CFTR | P13569 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL812065 | 0.81 | KDM4E (0.59) | TDP1L3MBTL1PKMMAP2K1KDM4E | |
| SCHEMBL107721 | 0.79 | KDM4E (0.57) | TDP1L3MBTL1PKMMAP2K1KDM4E | |
| SCHEMBL27819878 | 0.79 | P2RX7 (0.66) | TDP1L3MBTL1PKMMAP2K1KDM4E | |
| SCHEMBL162558 | 0.79 | TDP1 (0.57) | TDP1L3MBTL1PKMMAP2K1KDM4E | |
| SCHEMBL31185958 | 0.79 | KDM4E (0.57) | TDP1L3MBTL1PKMMAP2K1KDM4E | |
| SCHEMBL69990 | 0.79 | L3MBTL1 (0.62) | TDP1L3MBTL1PKMMAP2K1KDM4E | |
| SCHEMBL29416324 | 0.79 | L3MBTL1 (0.62) | TDP1L3MBTL1PKMMAP2K1KDM4E | |
| SCHEMBL1248162 | 0.79 | P2RX7 (0.66) | TDP1L3MBTL1PKMMAP2K1KDM4E | |
| SCHEMBL111436 | 0.78 | TDP1 (0.55) | TDP1L3MBTL1PKMMAP2K1KDM4E | |
| SCHEMBL1807370 | 0.78 | TDP1 (0.55) | TDP1L3MBTL1PKMMAP2K1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110213156-A1 | 5-MEMBERED HETEROCYCLIC COMPOUND | RESEARCH FOUNDATION ITSUU LABORATORY (JP) | 2011-09-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110213156-A1 | 5-MEMBERED HETEROCYCLIC COMPOUND | RXRA, RXRG, RXRB | TDP1 4723/4885L3MBTL1 4273/4885PKM 2977/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.