SCHEMBL29416324

SCHEMBL29416324

COC(=O)c1cccnc1C(=O)OC

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.62
TDP1 Q9NUW8 1/20 0.57
MAP2K1 Q02750 1/20 0.54
KDM4E B2RXH2 6/20 0.54
ALDH1A1 P00352 6/20 0.54
POLB P06746 2/20 0.52
ATM Q13315 1/20 0.52
PKM P14618 1/20 0.51
TSHR P16473 2/20 0.50
ALOX15 P16050 2/20 0.50
LMNA P02545 1/20 0.50
CYP3A4 P08684 1/20 0.50
MAPT P10636 1/20 0.50
BLM P54132 1/20 0.50
AGER Q15109 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
CFTR P13569 1/20 0.48
HSD17B10 Q99714 1/20 0.48
CNR2 P34972 1/20 0.48
HTT P42858 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL69990 1.00 L3MBTL1 (0.62) L3MBTL1TDP1MAP2K1KDM4EALDH1A1
SCHEMBL2800466 0.89 L3MBTL1 (0.54) L3MBTL1TDP1MAP2K1KDM4EALDH1A1
SCHEMBL30503698 0.89 KDM4E (0.67) L3MBTL1TDP1MAP2K1KDM4EALDH1A1
SCHEMBL29559479 0.89 KDM4E (0.67) L3MBTL1TDP1MAP2K1KDM4EALDH1A1
SCHEMBL9632137 0.89 L3MBTL1 (0.58) L3MBTL1TDP1MAP2K1KDM4EALDH1A1
SCHEMBL519094 0.89 KDM4E (0.67) L3MBTL1TDP1MAP2K1KDM4EALDH1A1
SCHEMBL519095 0.89 KDM4E (0.67) L3MBTL1TDP1MAP2K1KDM4EALDH1A1
SCHEMBL13485365 0.87 L3MBTL1 (0.57) L3MBTL1TDP1MAP2K1KDM4EALDH1A1
SCHEMBL2372518 0.87 L3MBTL1 (0.57) L3MBTL1TDP1MAP2K1KDM4EALDH1A1
SCHEMBL30452153 0.87 L3MBTL1 (0.57) L3MBTL1TDP1MAP2K1KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117756780-A Efficient and clean treatment method for synthesizing imazamox 江苏扬农化工股份有限公司 2024-03-26 CN claimed
CN-115322350-A Degradable bio-based polyester and preparation method and application thereof 苏州瀚海新材料有限公司 2022-11-11 CN claimed
CN-114478477-A Synthesis process of imazamox 江苏中旗科技股份有限公司 2022-05-13 CN claimed
EP-3983416-B1 CGRP ANTAGONIST COMPOUNDS NXERA PHARMA UK LTD (GB) 2025-09-03 EP disclosed
CN-120271500-A Novel compound containing pyridine-2, 3-dicarboxylic acid dimethyl ester group and preparation method thereof 山东龙华生物股份有限公司 2025-07-08 CN disclosed
CN-120271500-A Novel compound containing pyridine-2, 3-dicarboxylic acid dimethyl ester group and preparation method thereof 山东龙华生物股份有限公司 2025-07-08 CN disclosed
US-12344621-B2 CGRP antagonist compounds NXERA PHARMA UK LIMITED (GB) 2025-07-01 US disclosed
CN-115703776-B Plasmin inhibitor, preparation method and application thereof 赛诺哈勃药业(成都)有限公司 2025-06-17 CN disclosed
CN-119954801-A TAU protein targeting compounds and related methods of use 阿尔维纳斯运营股份有限公司 2025-05-09 CN disclosed
CN-119504703-A Methoxydim plant method for purifying smoke 湖北泰盛化工有限公司 2025-02-25 CN disclosed
CN-114867727-B TAU protein targeting compounds and related methods of use 阿尔维纳斯运营股份有限公司 2025-02-21 CN disclosed
CN-114728977-A Pyrimidone derivatives containing two fused bicyclic rings 巴斯夫欧洲公司 2022-07-08 CN disclosed
WO-2022143911-A1 PLASMIN INHIBITOR, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 赛诺哈勃药业(成都)有限公司 2022-07-07 WO disclosed
EP-3999182-A1 TAU-PROTEIN TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE Arvinas Operations, Inc. (US) 2022-05-25 EP disclosed
CN-114478477-A Synthesis process of imazamox 江苏中旗科技股份有限公司 2022-05-13 CN disclosed
CN-114478477-A Synthesis process of imazamox 江苏中旗科技股份有限公司 2022-05-13 CN disclosed
EP-3983417-A1 CGRP ANTAGONIST COMPOUNDS Heptares Therapeutics Limited (GB) 2022-04-20 EP disclosed
EP-3983416-A1 CGRP ANTAGONIST COMPOUNDS Heptares Therapeutics Limited (GB) 2022-04-20 EP disclosed
CN-114245798-A CGRP antagonist compounds 赫普泰雅治疗有限公司 2022-03-25 CN disclosed
CN-114245797-A CGRP antagonist compounds 赫普泰雅治疗有限公司 2022-03-25 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12344621-B2 CGRP antagonist compounds CALCRL, CALCR, CALCA L3MBTL1 2146/4885TDP1 1158/4885MAP2K1 4422/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.