SCHEMBL24673252

SCHEMBL24673252

C[C@H](O)CN1CCN(CP(=O)(O)O)CCN([C@H](CO)[C@H](O)CO)CC1

nearest known ligand 0.33

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 1/20 0.32
DRD4 P21917 1/20 0.32
DRD3 P35462 1/20 0.32
SLC6A3 Q01959 1/20 0.32
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
POLB P06746 1/20 0.31
MAPT P10636 1/20 0.31
ATM Q13315 1/20 0.31
ANPEP P15144 1/20 0.30
ERAP2 Q6P179 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24673258 0.90 MAPT (0.33) KDM4EALDH1A1POLBMAPT
SCHEMBL24673208 0.87 KDM4E (0.31) KDM4EALDH1A1POLB
SCHEMBL7045053 0.83 KDM4E (0.41) DRD2DRD4DRD3SLC6A3KDM4E
SCHEMBL22014101 0.83 KDM4E (0.41) DRD2DRD4DRD3SLC6A3KDM4E
Calcobutrol SCHEMBL28960371 0.79 SLC6A9 (0.37) DRD2DRD4DRD3SLC6A3MAPT
SCHEMBL24672263 0.74 LMNA (0.38) POLBMAPT
SCHEMBL3971329 0.74 KDM4E (0.39) KDM4EALDH1A1POLBMAPTANPEP
SCHEMBL21066192 0.74 HSD17B10 (0.36) KDM4EALDH1A1POLBMAPTANPEP
SCHEMBL24672258 0.72 KDM4E (0.51) KDM4EALDH1A1POLBATM
SCHEMBL24673200 0.70 PKM (0.43) DRD2DRD3KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022204065-A1 IRON(III) MACROCYCLIC COMPLEXES WITH MIXED HYROXYL PENDANTS AS MRI CONTRAST AGENTS THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2022-09-29 WO disclosed