SCHEMBL24673258

SCHEMBL24673258

O=P(O)(O)CN1CCN([C@H](CO)[C@H](O)CO)CCN([C@H](CO)[C@H](O)CO)CC1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.33
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24673252 0.90 DRD2 (0.32) MAPTKDM4EALDH1A1POLB
SCHEMBL24673208 0.76 KDM4E (0.31) KDM4EALDH1A1POLB
SCHEMBL24673209 0.75 PGK1 (0.41) KDM4EALDH1A1
SCHEMBL24673192 0.74
SCHEMBL336769 0.74 MAPT (0.52) MAPTKDM4EALDH1A1POLB
SCHEMBL3966649 0.74 MAPT (0.52) MAPTKDM4EALDH1A1POLB
SCHEMBL23532238 0.74 MAPT (0.52) MAPTKDM4EALDH1A1POLB
SCHEMBL23802704 0.74 SLC6A9 (0.43) MAPT
SCHEMBL23802703 0.74 SLC6A9 (0.43) MAPT
Calcobutrol SCHEMBL20540234 0.74 SLC6A9 (0.43) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022204065-A1 IRON(III) MACROCYCLIC COMPLEXES WITH MIXED HYROXYL PENDANTS AS MRI CONTRAST AGENTS THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2022-09-29 WO disclosed