Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INPP5A | Q14642 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | ACLY | P53396 | 1/20 | 0.31 |
| ▸ | ADH1B | P00325 | 1/20 | 0.31 |
| ▸ | ADH1C | P00326 | 1/20 | 0.31 |
| ▸ | ADH1A | P07327 | 1/20 | 0.31 |
| ▸ | ADH4 | P08319 | 1/20 | 0.31 |
| ▸ | ADH7 | P40394 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP3 | P08254 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5648100 | 0.97 | INPP5A (0.50) | INPP5AALOX5EPHX1HPGDKMT2A | |
| SCHEMBL6957998 | 0.97 | INPP5A (0.50) | INPP5AALOX5EPHX1HPGDKMT2A | |
| Hydrochloric Acid SCHEMBL27851279 | 0.97 | INPP5A (0.56) | INPP5AALOX5EPHX1HPGDKMT2A | |
| SCHEMBL28296964 | 0.97 | INPP5A (0.50) | INPP5AALOX5EPHX1HPGDKMT2A | |
| SCHEMBL5669891 | 0.97 | INPP5A (0.50) | INPP5AALOX5EPHX1HPGDKMT2A | |
| SCHEMBL6965666 | 0.95 | INPP5A (0.48) | INPP5AALOX5EPHX1HPGDKMT2A | |
| Hydrochloric Acid SCHEMBL28059252 | 0.95 | INPP5A (0.54) | INPP5AALOX5EPHX1HPGDKMT2A | |
| SCHEMBL7402518 | 0.95 | INPP5A (0.48) | INPP5AALOX5EPHX1HPGDKMT2A | |
| SCHEMBL3961106 | 0.94 | — | — | |
| Hydrochloric Acid SCHEMBL28307160 | 0.92 | INPP5A (0.56) | INPP5AALOX5ACLYADH1BADH1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112574175-B | Quinoline compound, preparation method and application thereof | 南京长澳医药科技有限公司 | 2023-11-14 | — | — | CN | disclosed |
| WO-2022070288-A1 | NITROGEN-CONTAINING BICYCLIC COMPOUND | 旭化成ファーマ株式会社 | 2022-04-07 | — | — | WO | disclosed |
| CN-112574175-A | Quinoline compound, preparation method and application thereof | 上海阳帆医药科技有限公司 | 2021-03-30 | — | — | CN | disclosed |
| WO-2021039800-A1 | METHOD FOR PREPARING ENANTIOMER OF SULFOXIDE COMPOUND, AND SYSTEM FOR PREPARING ENANTIOMER | 学校法人東京理科大学 | 2021-03-04 | — | — | WO | disclosed |
| US-20190047968-A1 | 6-ACYL-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE AND HERBICIDES | FMC CORP (US) | 2019-02-14 | — | — | US | disclosed |
| US-10081608-B2 | 6-acyl-1,2,4-triazine-3,5-dione derivative and herbicides | FMC CORPORATION (US) | 2018-09-25 | — | — | US | disclosed |
| EP-2041825-B1 | FUEL CELLS | ACAL ENERGY LTD (GB) | 2017-11-22 | — | — | EP | disclosed |
| US-20170129861-A1 | 6-ACYL-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE AND HERBICIDES | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2017-05-11 | — | — | US | disclosed |
| US-9573909-B2 | 6-acyl-1,2,4-triazine-3,5-dione derivative and herbicides | FMC CORPORATION (US) | 2017-02-21 | — | — | US | disclosed |
| EP-3020709-A1 | 6-ACYL-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE AND HERBICIDES | FMC CORPORATION (US) | 2016-05-18 | — | — | EP | disclosed |
| US-20100113410-A1 | PYRAZOLOPYRIMIDINE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2010-05-06 | — | — | US | disclosed |
| EP-2065388-A1 | PYRAZOLOPYRIMIDINE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2009-06-03 | — | — | EP | disclosed |
| CN-101421257-A | Agents that disrupt cellular replication and their use in inhibiting pathological conditions | EUROPEAN MOLECULAR BIOLOGY LAB EMBL (DE) | 2009-04-29 | — | — | CN | disclosed |
| US-20080182906-A1 | Novel Specific Caspase-10 Inhibitors | MERCK PATENT GMBH (DE) | 2008-07-31 | — | — | US | disclosed |
| EP-1881960-A1 | NOVEL SPECIFIC CASPASE-10 INHIBITORS | Merck Patent GmbH (DE) | 2008-01-30 | — | — | EP | disclosed |
| WO-2006114190-A1 | NOVEL SPECIFIC CASPASE-10 INHIBITORS | MERCK PATENT GMBH (DE) | 2006-11-02 | — | — | WO | disclosed |
| EP-0635485-B1 | TETRAHYDROPHTHALAMIDE DERIVATIVE, INTERMEDIATE FOR PRODUCING THE SAME, PRODUCTION OF BOTH, AND HERBICIDE CONTAINING THE SAME AS ACTIVE INGREDIENT | SAGAMI CHEM RES (JP) | 1997-06-11 | — | — | EP | disclosed |
| US-5554581-A | Tetrahydrophthalamide derivative, intermediate for producing the same, production of both, and herbicide containing the same as active ingredient | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1996-09-10 | — | — | US | disclosed |
| US-5506190-A | Tetrahydrophthalamide derivative, intermediate for producing the same, production of both, and herbicide containing the same as active ingredient | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1996-04-09 | — | — | US | disclosed |
| EP-0635485-A1 | TETRAHYDROPHTHALAMIDE DERIVATIVE, INTERMEDIATE FOR PRODUCING THE SAME, PRODUCTION OF BOTH, AND HERBICIDE CONTAINING THE SAME AS ACTIVE INGREDIENT | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1995-01-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080182906-A1 | Novel Specific Caspase-10 Inhibitors | CASP10, CASP1, CASP2 | INPP5A 3710/4885ALOX5 1715/4885EPHX1 2501/4885 |
| US-10081608-B2 | 6-acyl-1,2,4-triazine-3,5-dione derivative and herbicides | DDT, AADAC, DAZAP1 | INPP5A 213/4885ALOX5 448/4885EPHX1 1464/4885 |
| US-20170129861-A1 | 6-ACYL-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE AND HERBICIDES | DDT, AADAC, DAZAP1 | INPP5A 213/4885ALOX5 448/4885EPHX1 1464/4885 |
| US-20100113410-A1 | PYRAZOLOPYRIMIDINE DERIVATIVE | HSP90AB1, HSP90B1, HSP90AA1 | INPP5A 2756/4885ALOX5 4440/4885EPHX1 2904/4885 |
| US-20190047968-A1 | 6-ACYL-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE AND HERBICIDES | DDT, AADAC, DAZAP1 | INPP5A 213/4885ALOX5 448/4885EPHX1 1464/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.