SCHEMBL2467446

SCHEMBL2467446

CCc1[c]c(CC)cc(Cc2cc(CC)[c]c(CC)c2)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL147391 0.86 PTGS2 (0.37)
SCHEMBL2466339 0.85
SCHEMBL5050077 0.84 PTGS2 (0.33)
SCHEMBL28453454 0.83 PTGS2 (0.36)
SCHEMBL27382724 0.79 LOXL2 (0.32)
SCHEMBL28344918 0.77 ESR1 (0.38)
SCHEMBL28090050 0.75 TAAR1 (0.33)
SCHEMBL28641769 0.75 HPGD (0.47)
SCHEMBL263267 0.74 NOS3 (0.34)
SCHEMBL15068068 0.74 PTGS2 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1879963-B1 POLYAMIDE RESIN COMPOSITION JTEKT CORP (JP) 2018-01-03 EP disclosed
EP-2371903-A2 Gear for an electric power steering device the gear comprising a polyamide composition E. I. du Pont de Nemours and Company (US) 2011-10-05 EP disclosed
US-7728071-B2 Gear for electric power steering device E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-06-01 US disclosed
EP-2018307-A1 WORM GEAR FOR ELECTRIC POWER STEERING DEVICE E.I. DU PONT DE NEMOURS AND COMPANY (US) 2009-01-28 EP disclosed
EP-1879963-A1 POLYAMIDE RESIN COMPOSITION E.I. DUPONT DE NEMOURS AND COMPANY (US) 2008-01-23 EP disclosed
WO-2007133205-A1 WORM GEAR FOR ELECTRIC POWER STEERING DEVICE E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-11-22 WO disclosed
US-20070265392-A1 Gear for electric power steering device JTEKT CORPORATION (JP) 2007-11-15 US disclosed
US-20070021558-A1 Polyamide resin composition SHINOHARA KENICHI 2007-01-25 US disclosed
WO-2006124659-A1 POLYAMIDE RESIN COMPOSITION E. I. DU PONT DE NEMOURS AND COMPANY (US) 2006-11-23 WO disclosed
US-20040010094-A1 Injection moldable polyamide resin compositions containing poly carbo-di-imides and articles made therefrom E.I. DU PONT DE NEMOURS AND COMPANY 2004-01-15 US disclosed
WO-2003089518-A1 INJECTION MOLDABLE POLYAMIDE RESIN COMPOSITIONS CONTAINING POLY CARBO-DI-IMIDES AND ARTICLES MADE THEREFROM E.I. DU PONT DE NEMOURS AND COMPANY (US) 2003-10-30 WO disclosed