Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4445540 | 0.83 | LMNA (0.44) | LMNAALDH1A1 | |
| SCHEMBL7536748 | 0.81 | LMNA (0.46) | LMNAALDH1A1 | |
| SCHEMBL4450790 | 0.74 | LMNA (0.34) | LMNAALDH1A1 | |
| Acetic Acid SCHEMBL7164585 | 0.73 | ALDH1A1 (0.33) | LMNAALDH1A1CA2CA1 | |
| SCHEMBL7527544 | 0.72 | LMNA (0.35) | LMNAALDH1A1 | |
| Acetic Acid SCHEMBL377225 | 0.66 | CA1 (0.53) | LMNAALDH1A1CA2CA1 | |
| Acetic Acid SCHEMBL540581 | 0.66 | ALDH1A1 (0.41) | LMNAALDH1A1 | |
| Acetic Acid SCHEMBL3683183 | 0.66 | ALDH1A1 (0.41) | LMNAALDH1A1 | |
| Acetic Acid SCHEMBL10798034 | 0.64 | LMNA (0.44) | LMNAALDH1A1 | |
| Phosphoric Acid SCHEMBL6739275 | 0.63 | TP53 (0.43) | LMNACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8013085-B2 | addition polymerization of ethylenically unsaturated monomers in an aqueous medium in the presence of polymer particles and at least one dispersant; polymer powders used as additives in adhesives, seals, plasters, renderings, paper coatings or paints | BASF AKTIENGESELLSCHAFT (DE) | 2011-09-06 | — | — | US | disclosed |
| US-20060264558-A1 | Method for the production of an aqueous polymer dispersion | BASF AKTIENGESELLSCHAFT (DE) | 2006-11-23 | — | — | US | disclosed |