SCHEMBL4450790

SCHEMBL4450790

O=C(O)CC(CO)CCCPCCCPCCCC(CO)CC(=O)O

nearest known ligand 0.34

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.34
SLC22A6 Q4U2R8 1/20 0.31
CACNA2D1 P54289 2/20 0.31
CACNB3 P54284 1/20 0.31
CACNA1C Q13936 1/20 0.31
PGR P06401 1/20 0.31
ADRA1A P35348 1/20 0.31
HTR2B P41595 1/20 0.31
CACNA2D2 Q9NY47 1/20 0.31
GSTK1 Q9Y2Q3 1/20 0.31
ALDH1A1 P00352 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7527544 0.98 LMNA (0.35) LMNASLC22A6CACNA2D1CACNB3CACNA1C
SCHEMBL4445540 0.80 LMNA (0.44) LMNAALDH1A1
SCHEMBL7536748 0.78 LMNA (0.46) LMNAALDH1A1
SCHEMBL4952556 0.77 GPR84 (0.41) LMNASLC22A6CACNA2D1CACNB3CACNA1C
SCHEMBL5112958 0.75 ALDH1A1 (0.58) LMNASLC22A6ALDH1A1TDP1
SCHEMBL4654992 0.75 ALDH1A1 (0.58) LMNASLC22A6ALDH1A1TDP1
SCHEMBL5104868 0.75 ALDH1A1 (0.58) LMNASLC22A6ALDH1A1TDP1
SCHEMBL7820083 0.75 SLC22A6 (0.33) LMNASLC22A6CACNA2D1CACNB3CACNA1C
Acetic Acid SCHEMBL2467469 0.74 LMNA (0.38) LMNAALDH1A1
SCHEMBL317762 0.73 LMNA (0.61) LMNASLC22A6ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090030093-A1 METHOD FOR EMULSION POLYMERISATION OF OLEFINS BASF AKTIENGESSELLSCHAFT (DE) 2009-01-29 US disclosed
US-7417098-B2 Method for emulsion polymerisation of olefins BASF SE (DE) 2008-08-26 US disclosed
US-20080182915-A1 METHOD FOR EMULSION POLYMERISATION OF OLEFINS BASF AKTIENGESELLSCHAFT (DE) 2008-07-31 US disclosed
EP-1636282-B1 METHOD FOR THE PRODUCTION OF AN AQUEOUS POLYMER DISPERSION BASF AG (DE) 2007-05-02 EP disclosed
US-20070043163-A1 Method for emulsion polymerisation of olefins BASF AKTIENGESELLSCHAFT (DE) 2007-02-22 US disclosed
EP-1196475-B1 METHOD FOR THE PRODUCTION OF OLEFIN/CARBON MONOXIDE COPOLYMERS BASF AG (DE) 2005-07-20 EP disclosed
US-6670443-B1 Feeding ethylene in pulses BASF AKTIENGESELLSCHAFT (DE) 2003-12-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080182915-A1 METHOD FOR EMULSION POLYMERISATION OF OLEFINS SQLE, PHOSPHO1, ALOX15 LMNA 4276/4885SLC22A6 2599/4885CACNA2D1 3275/4885
US-20070043163-A1 Method for emulsion polymerisation of olefins PHOSPHO1, SQLE, ALOX15 LMNA 4462/4885SLC22A6 2460/4885CACNA2D1 3121/4885
US-20090030093-A1 METHOD FOR EMULSION POLYMERISATION OF OLEFINS PHOSPHO1, SQLE, ALOX15 LMNA 4462/4885SLC22A6 2460/4885CACNA2D1 3121/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.