Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23986828 | 0.98 | CA12 (0.42) | CHRM2CHRM4CHRM5CHRM1CHRNB2 | |
| SCHEMBL22787027 | 0.85 | LMNA (0.50) | CHRM2CHRM4CHRM5CHRM1CHRNB2 | |
| SCHEMBL16280975 | 0.83 | LMNA (0.48) | CHRM2CHRM4CHRM5CHRM1CHRNB2 | |
| SCHEMBL27347790 | 0.83 | LMNA (0.48) | CHRM2CHRM4CHRM5CHRM1CHRNB2 | |
| SCHEMBL25868589 | 0.82 | KDM7A (0.48) | CHRM2CHRM4CHRM5CHRM1CHRNB2 | |
| SCHEMBL23007709 | 0.82 | OPRK1 (0.53) | CHRM2CHRM4CHRM5CHRM1CHRNB2 | |
| SCHEMBL22623222 | 0.79 | DNM1 (0.48) | CA12CA1CA2CA9DNM1 | |
| SCHEMBL22623295 | 0.79 | DNM1 (0.48) | CA12CA1CA2CA9DNM1 | |
| SCHEMBL4774589 | 0.78 | — | — | |
| SCHEMBL30997594 | 0.78 | KMT2A (0.52) | CHRM2CHRM4CHRM5CHRM1CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022223022-A1 | FUSED-RING HETEROCYCLE DERIVATIVE AND MEDICAL APPLICATION THEREOF | 四川海思科制药有限公司 | 2022-10-27 | — | — | WO | disclosed |