Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 8/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | JUN | P05412 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 2/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.31 |
| ▸ | HEXA | P06865 | 1/20 | 0.30 |
| ▸ | HEXB | P07686 | 1/20 | 0.30 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25163413 | 0.79 | HCRTR1 (0.34) | HCRTR1HCRTR2JUNNFKB1NFKB2 | |
| SCHEMBL30206058 | 0.78 | HEXA (0.40) | HCRTR1HCRTR2MTORPIK3CAHEXA | |
| SCHEMBL31336794 | 0.75 | GAA (0.36) | HCRTR1TRPV4 | |
| SCHEMBL24675335 | 0.71 | TRPV4 (0.33) | TRPV4 | |
| SCHEMBL11223672 | 0.71 | CCR4 (0.38) | — | |
| SCHEMBL22877075 | 0.67 | HCRTR1 (0.51) | HCRTR1HCRTR2 | |
| SCHEMBL30851661 | 0.67 | USP7 (0.34) | PIK3CATRPV4 | |
| SCHEMBL27223206 | 0.67 | PDXK (0.34) | — | |
| SCHEMBL16248176 | 0.67 | JUN (0.35) | JUNNFKB1NFKB2RELAHEXA | |
| SCHEMBL24675607 | 0.67 | TRPV4 (0.31) | TRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022223022-A1 | FUSED-RING HETEROCYCLE DERIVATIVE AND MEDICAL APPLICATION THEREOF | 四川海思科制药有限公司 | 2022-10-27 | — | — | WO | disclosed |