SCHEMBL331944

SCHEMBL331944

C[C@H]1O[C@@H](n2cc(F)c(N)nc2=O)[C@H](O)[C@@H]1O

nearest known ligand 0.56

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.56
TSHR P16473 1/20 0.56
MAPT P10636 1/20 0.56
PMP22 Q01453 1/20 0.56
HBB P68871 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
ALB P02768 1/20 0.47
ADK P55263 10/20 0.46
ADORA3 P0DMS8 1/20 0.45
THRB P10828 1/20 0.40
MTOR P42345 1/20 0.40
MDM2 Q00987 1/20 0.40
NCOA1 Q15788 1/20 0.40
NCOA3 Q9Y6Q9 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12302008 1.00 LMNA (0.56) LMNATSHRMAPTPMP22HBB
SCHEMBL13621266 1.00 LMNA (0.56) LMNATSHRMAPTPMP22HBB
SCHEMBL12029778 1.00 LMNA (0.56) LMNATSHRMAPTPMP22HBB
SCHEMBL10041945 1.00 LMNA (0.56) LMNATSHRMAPTPMP22HBB
SCHEMBL15119375 1.00 LMNA (0.56) LMNATSHRMAPTPMP22HBB
SCHEMBL331945 1.00 LMNA (0.56) LMNATSHRMAPTPMP22HBB
SCHEMBL2467656 1.00 LMNA (0.56) LMNATSHRMAPTPMP22HBB
SCHEMBL19657131 1.00 LMNA (0.56) LMNATSHRMAPTPMP22HBB
SCHEMBL10013535 1.00 LMNA (0.56) LMNATSHRMAPTPMP22HBB
SCHEMBL13126803 1.00 LMNA (0.56) LMNATSHRMAPTPMP22HBB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 848 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250017931-A1 METHODS OF PERSONALIZING CANCER TREATMENT PROCESSA PHARMACEUTICALS, INC., (US) 2025-01-16 US claimed
US-20240299554-A1 PRODRUGS WITH 1-(DISULFANYL)ALKYLOXY-CARBONYL UNITS PHARMACYTICS B.V. (NL) 2024-09-12 US claimed
EP-4359419-A1 PRODRUGS WITH 1-(DISULFANYL)ALKYLOXY-CARBONYL UNITS Pharmacytics B.V. (NL) 2024-05-01 EP claimed
CN-117858882-A Prodrugs having 1- (disulfanyl) alkoxy-carbonyl units 药物有限公司 2024-04-09 CN claimed
CN-117603286-A Preparation and application of lysosome-targeted aging cell removal prodrug 江南大学 2024-02-27 CN claimed
EP-4260874-A1 CLEAVABLE POLYMER DRUG CONJUGATES RS Arastirma Egitim Danismanlik Ilac Sanayi Ticaret Anonim Sirketi (TR) 2023-10-18 EP claimed
EP-3478323-B1 CLEAVABLE POLYMER DRUG CONJUGATES RS ARASTIRMA EGITIM DANISMANLIK ILAC SANAYI TICARET ANONIM SIRKETI (TR) 2023-09-27 EP claimed
US-20230172960-A1 TOPICAL CAPECITABINE FOR THE TREATMENT OF HYPERPROLIFERATIVE SKIN CONDITIONS TARO PHARMACEUTICAL INDUSTRIES LTD. (IL) 2023-06-08 US claimed
US-20230023537-A1 DELIVERY SYSTEMS FOR CONTROLLED DRUG RELEASE LADRX CORPORATION 2023-01-26 US claimed
US-11559541-B2 Topical capecitabine for the treatment of hyperproliferative skin conditions TARO PHARMACEUTICAL INDUSTRIES LTD. (IL) 2023-01-24 US claimed
EP-1461122-A2 TREATMENT OF GENITOURINARY TRACT DISORDERS Control Delivery Systems, Inc. (US) 2004-09-29 EP claimed
EP-1448231-A1 TOPICAL DELIVERY OF CODRUGS Control Delivery Systems, Inc. (US) 2004-08-25 EP claimed
US-20030203030-A1 Polymeric gel delivery system for pharmaceuticals CONTROL DELIVERY SYSTEMS, INC. 2003-10-30 US claimed
US-20030170286-A1 Treatment of genitourinary tract disorders CONTROL DELIVERY SYSTEMS, INC. 2003-09-11 US claimed
WO-2003061626-A1 POLYMERIC GEL SYSTEM FOR THE CONTROLLED DELIVERY OF CODRUGS CONTROL DELIVERY SYSTEMS, INC. (US) 2003-07-31 WO claimed
US-20030118528-A1 Topical delivery of codrugs CONTROL DELIVERY SYSTEMS, INC. 2003-06-26 US claimed
WO-2003049804-A2 TREATMENT OF GENITOURINARY TRACT DISORDERS CONTROL DELIVERY SYSTEMS INC. (US) 2003-06-19 WO claimed
WO-2003043657-A1 TOPICAL DELIVERY OF CODRUGS CONTROL DELIVERY SYSTEMS, INC. (US) 2003-05-30 WO claimed
EP-0316704-B1 Fluorocytidine derivatives, their preparation and medical preparations containing them HOFFMANN LA ROCHE (CH) 1995-07-12 EP claimed
US-4071680-A ANTITUMOR AGENTS HOFFMANN-LA ROCHE INC. (US) 1978-01-31 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030118528-A1 Topical delivery of codrugs DSG1, CCR7, CUTA LMNA 1847/4885TSHR 4725/4885MAPT 832/4885
US-20240299554-A1 PRODRUGS WITH 1-(DISULFANYL)ALKYLOXY-CARBONYL UNITS SI, SULT1E1, SULT1A1 LMNA 3632/4885TSHR 3169/4885MAPT 3457/4885
US-20030170286-A1 Treatment of genitourinary tract disorders GLS, FOLH1, KLK3 LMNA 3621/4885TSHR 2871/4885MAPT 2064/4885
US-20230023537-A1 DELIVERY SYSTEMS FOR CONTROLLED DRUG RELEASE ABCB11, SLC10A1, SLC5A1 LMNA 3041/4885TSHR 1801/4885MAPT 565/4885
US-20030203030-A1 Polymeric gel delivery system for pharmaceuticals MMP1, IL6, CD44 LMNA 3997/4885TSHR 4559/4885MAPT 2016/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.