Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | FPR2 | P25090 | 2/20 | 0.37 |
| ▸ | GLS | O94925 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.36 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 2/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | STS | P08842 | 1/20 | 0.35 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24676959 | 0.84 | DDB1 (0.37) | NR1H2KDM4EUSP30FPR2MAPT | |
| SCHEMBL29001993 | 0.76 | USP30 (0.43) | NR1H2KDM4EUSP30FPR2HPGD | |
| SCHEMBL16717787 | 0.76 | GPR119 (0.40) | NR1H2KDM4EUSP30FPR2MAPT | |
| SCHEMBL9947823 | 0.75 | HSD11B1 (0.44) | NR1H2KDM4EUSP30MAPTTHRB | |
| SCHEMBL25483611 | 0.73 | KDM1A (0.40) | — | |
| SCHEMBL9947911 | 0.73 | GPR119 (0.51) | MAPT | |
| SCHEMBL21858824 | 0.73 | GLS (0.43) | KDM4EUSP30FPR2GLSMAPT | |
| SCHEMBL23149096 | 0.73 | KDM4E (0.41) | NR1H2KDM4EUSP30FPR2MAPT | |
| SCHEMBL26132929 | 0.73 | GPR119 (0.44) | NR1H2KDM4EUSP30GLSHPGD | |
| SCHEMBL23306607 | 0.73 | KDM4E (0.49) | KDM4EMAPTTHRBHPGDSTS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022155941-A1 | CDK2 INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2022-07-28 | — | — | WO | disclosed |