Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.34 |
| ▸ | TRPV3 | Q8NET8 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | STS | P08842 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24676849 | 0.84 | NR1H2 (0.39) | DDB1CRBNNR1H2RORCKDM4E | |
| SCHEMBL24676714 | 0.75 | DYRK2 (0.35) | NR1H2USP30TRPV3HDAC6MAP3K14 | |
| SCHEMBL24677053 | 0.74 | NR1H2 (0.40) | NR1H2RORCKDM4EUSP30MAPT | |
| SCHEMBL16717787 | 0.73 | GPR119 (0.40) | NR1H2RORCKDM4EUSP30MAPT | |
| SCHEMBL29001993 | 0.73 | USP30 (0.43) | NR1H2KDM4EUSP30HPGDFPR2 | |
| SCHEMBL9947911 | 0.71 | GPR119 (0.51) | MAPT | |
| SCHEMBL26132929 | 0.70 | GPR119 (0.44) | NR1H2KDM4EUSP30HPGD | |
| SCHEMBL23149096 | 0.70 | KDM4E (0.41) | DDB1CRBNNR1H2RORCKDM4E | |
| SCHEMBL9947823 | 0.69 | HSD11B1 (0.44) | NR1H2KDM4EUSP30MAPTTHRB | |
| SCHEMBL29858289 | 0.69 | NPC1 (0.46) | KDM4EUSP30MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022155941-A1 | CDK2 INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2022-07-28 | — | — | WO | disclosed |