SCHEMBL2468006

SCHEMBL2468006

O=C(O)CCOc1ccc(O)cc1

nearest known ligand 0.69

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.69
MMP2 P08253 1/20 0.59
FFAR1 O14842 3/20 0.51
LMNA P02545 1/20 0.51
TSHR P16473 1/20 0.51
ALB P02768 1/20 0.51
LTA4H P09960 2/20 0.50
ESR1 P03372 1/20 0.50
NR5A1 Q13285 1/20 0.50
PPARA Q07869 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1271045 0.90 ESR1 (0.59) L3MBTL1FFAR1ALBLTA4HESR1
SCHEMBL2158826 0.86 ALB (0.68) ALBESR1NR5A1PPARA
SCHEMBL7747968 0.86 ALB (0.68) ALBESR1NR5A1PPARA
SCHEMBL12534514 0.86 ALB (0.68) ALBESR1NR5A1PPARA
SCHEMBL2494017 0.85 ALB (0.66) ALBESR1NR5A1PPARA
SCHEMBL9714152 0.83 L3MBTL1 (0.54) L3MBTL1MMP2FFAR1TSHRALB
SCHEMBL38674 0.83 L3MBTL1 (0.68) L3MBTL1MMP2FFAR1LMNATSHR
Mequinol SCHEMBL10533614 0.82 PDE4B (0.57) L3MBTL1FFAR1ALBESR1PPARA
SCHEMBL19043148 0.82 L3MBTL1 (0.72) L3MBTL1MMP2FFAR1LMNA
SCHEMBL1806524 0.82 L3MBTL1 (1.00) L3MBTL1MMP2FFAR1LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109651140-A A kind of synthetic method of cyhalofop-butyl active compound 江苏中旗科技股份有限公司 2019-04-19 CN claimed
US-9573965-B2 Process for the preparation of Dolutegravir AUROBINDO PHARMA LTD (IN) 2017-02-21 US claimed
US-20160108058-A1 An improved process for the preparation of Dolutegravir AUROBINDO PHARMA LTD. (IN) 2016-04-21 US claimed
JP-4776846-B2 2011-09-21 JP claimed
US-7078226-B1 Method for producing optically active amines BASF AKTIENGESELLSCHAFT (DE) 2006-07-18 US claimed
EP-1232279-B1 METHOD FOR PRODUCING OPTICALLY ACTIVE AMINES BASF AG (DE) 2005-03-02 EP claimed
EP-1232279-A2 METHOD FOR PRODUCING OPTICALLY ACTIVE AMINES BASF AKTIENGESELLSCHAFT (DE) 2002-08-21 EP claimed
WO-2001038292-A2 METHOD FOR PRODUCING OPTICALLY ACTIVE AMINES BASF AKTIENGESELLSCHAFT (DE) 2001-05-31 WO claimed
EP-0539274-B1 Method for the synthesis of aldehydes and of their derivatives RHONE POULENC CHIMIE (FR) 1996-04-10 EP claimed
EP-0383613-A2 Optically active lactate, derivatives thereof and processes of producing same Tosoh Corporation (JP) 1990-08-22 EP claimed
JP-2304076-A None JP disclosed
CN-119240903-A Wastewater treatment method based on improved wet oxidation reaction 南京工业大学 2025-01-03 CN disclosed
EP-4330382-A2 IN VITRO DRUGS FROM PRODRUGS AND USE THEREOF Brandenburgische Technische Universität Cottbus-Senftenberg (DE) 2024-03-06 EP disclosed
CN-115721995-A Production system and process of cyhalofop-butyl technical material 池州飞昊达化工有限公司 2023-03-03 CN disclosed
WO-2022229050-A2 IN VITRO DRUGS FROM PRODRUGS AND USE THEREOF BRANDENBURGISCHE TECHNISCHE UNIVERSITÄT COTTBUS-SENFTENBERG (DE) 2022-11-03 WO disclosed
EP-0139252-A2 Esterification of carboxylic acids containing phenol groups HOECHST AKTIENGESELLSCHAFT (DE) 1985-05-02 EP disclosed
EP-0138359-A2 Herbicidal Fluorophenoxyphenoxypropionates, derivatives thereof and related compounds THE DOW CHEMICAL COMPANY (US) 1985-04-24 EP disclosed
US-4336057-A Herbicides HOECHST AKTIENGESELLSCHAFT (DE) 1982-06-22 US disclosed
US-4325729-A Herbicidal and plant growth regulating pyridyloxy-phenoxy-propionic acid derivatives CIBA-GEIGY CORPORATION (US) 1982-04-20 US disclosed
WO-1979000094-A1 HERBICIDAL PYRIDINE COMPOUNDS ICI LTD (GB) 1979-03-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160108058-A1 An improved process for the preparation of Dolutegravir XDH, TBK1, POLR2H L3MBTL1 4146/4885MMP2 2839/4885FFAR1 1608/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.