Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSPO | P30536 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPY1R | P25929 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24683879 | 0.90 | SLC2A1 (0.39) | NPSR1ALDH1A1KDM4EGAAHPGD | |
| SCHEMBL24683186 | 0.90 | KMT2A (0.36) | NPSR1ALDH1A1KDM4EGAAHPGD | |
| SCHEMBL24682933 | 0.89 | CLK1 (0.36) | KDM4EGAALMNAMAPTKMT2A | |
| SCHEMBL29799740 | 0.88 | TSHR (0.38) | NPSR1ALDH1A1KDM4EGAAHPGD | |
| SCHEMBL24682207 | 0.88 | TSHR (0.38) | NPSR1ALDH1A1KDM4EGAAHPGD | |
| SCHEMBL24682963 | 0.87 | KMT2A (0.34) | NPSR1ALDH1A1KDM4EGAAHPGD | |
| SCHEMBL24683840 | 0.87 | KDM4E (0.34) | ALDH1A1KDM4EGAAHPGDTSPO | |
| SCHEMBL24683206 | 0.87 | LMNA (0.38) | ALDH1A1KDM4EGAAHPGDTSPO | |
| SCHEMBL24683203 | 0.86 | HSP90AA1 (0.39) | ALDH1A1GAATSPOLMNAMAPT | |
| SCHEMBL29799821 | 0.86 | HSP90AA1 (0.39) | ALDH1A1GAATSPOLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022173329-A1 | 2-ACETAMIDO-6-HYDROXY-BENZOTHIOPHENE DERIVATIVES WITH ANTIVIRAL ACTIVITY | Акционерное общество "Отисифарм" | 2022-08-18 | — | — | WO | disclosed |