Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.34 |
| ▸ | HSP90B1 | P14625 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | APAF1 | O14727 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24682191 | 0.90 | NPSR1 (0.36) | KMT2AMEN1HSP90AA1KDM4EALDH1A1 | |
| SCHEMBL24682933 | 0.89 | CLK1 (0.36) | KMT2AMEN1HSP90AA1HSP90B1RAB9A | |
| SCHEMBL24682827 | 0.87 | RIPK1 (0.34) | KMT2AMEN1HSP90AA1HSP90B1KDM4E | |
| SCHEMBL30664654 | 0.86 | HSP90AA1 (0.39) | KMT2AMEN1HSP90AA1HSP90B1RAB9A | |
| SCHEMBL24682815 | 0.86 | HSP90AA1 (0.39) | KMT2AMEN1HSP90AA1HSP90B1RAB9A | |
| SCHEMBL24683840 | 0.85 | KDM4E (0.34) | KMT2AMEN1HSP90AA1HSP90B1RAB9A | |
| SCHEMBL24682963 | 0.82 | KMT2A (0.34) | KMT2AMEN1HSP90AA1HSP90B1KDM4E | |
| SCHEMBL24683891 | 0.81 | TAAR1 (0.36) | KMT2AMEN1HSP90AA1HSP90B1RAB9A | |
| SCHEMBL29800145 | 0.81 | TAAR1 (0.36) | KMT2AMEN1HSP90AA1HSP90B1RAB9A | |
| SCHEMBL24683206 | 0.81 | LMNA (0.38) | KMT2AMEN1HSP90AA1HSP90B1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022173329-A1 | 2-ACETAMIDO-6-HYDROXY-BENZOTHIOPHENE DERIVATIVES WITH ANTIVIRAL ACTIVITY | Акционерное общество "Отисифарм" | 2022-08-18 | — | — | WO | disclosed |