Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.35 |
| ▸ | HSP90B1 | P14625 | 2/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSPO | P30536 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24682963 | 0.90 | KMT2A (0.34) | LMNAMAPTKDM4EHPGDTDP1 | |
| SCHEMBL24683840 | 0.89 | KDM4E (0.34) | LMNAMAPTKDM4EHPGDTDP1 | |
| SCHEMBL24683205 | 0.89 | LMNA (0.38) | LMNASMN1; SMN2MAPTKDM4EHPGD | |
| SCHEMBL29799927 | 0.89 | LMNA (0.38) | LMNASMN1; SMN2MAPTKDM4EHPGD | |
| SCHEMBL24682191 | 0.87 | NPSR1 (0.36) | LMNAMAPTKDM4EHPGDTDP1 | |
| SCHEMBL24683871 | 0.86 | POLB (0.37) | MAPTKDM4EHPGDTDP1HSP90AA1 | |
| SCHEMBL24682809 | 0.86 | ALDH1A1 (0.34) | LMNAMAPTKDM4EHPGDTDP1 | |
| SCHEMBL24683891 | 0.84 | TAAR1 (0.36) | LMNAMAPTKDM4EHPGDTDP1 | |
| SCHEMBL29800145 | 0.84 | TAAR1 (0.36) | LMNAMAPTKDM4EHPGDTDP1 | |
| SCHEMBL24682827 | 0.82 | RIPK1 (0.34) | MAPTKDM4EHPGDHSP90AA1HSP90B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022173329-A1 | 2-ACETAMIDO-6-HYDROXY-BENZOTHIOPHENE DERIVATIVES WITH ANTIVIRAL ACTIVITY | Акционерное общество "Отисифарм" | 2022-08-18 | — | — | WO | disclosed |