Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | TSPO | P30536 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29799740 | 1.00 | TSHR (0.38) | TSHRLMNANPY1RMAPK1AKT1 | |
| SCHEMBL24682191 | 0.88 | NPSR1 (0.36) | TSHRLMNANPY1RMAPK1AKT1 | |
| SCHEMBL30701647 | 0.87 | KMT2A (0.34) | TSHRLMNAMAPTKDM4ETDP1 | |
| SCHEMBL24683870 | 0.87 | KMT2A (0.34) | TSHRLMNAMAPTKDM4ETDP1 | |
| SCHEMBL24683226 | 0.86 | PDK1 (0.37) | HTTPDK1TSPOMAPTKMT2A | |
| SCHEMBL29800012 | 0.86 | PDK1 (0.37) | HTTPDK1TSPOMAPTKMT2A | |
| SCHEMBL30664670 | 0.85 | TSPO (0.35) | TSHRLMNANPY1RMAPK1AKT1 | |
| Hydrochloric Acid SCHEMBL29121147 | 0.84 | TSPO (0.34) | TSHRLMNANPY1RMAPK1AKT1 | |
| Hydrochloric Acid SCHEMBL30701654 | 0.84 | TSPO (0.34) | TSHRLMNANPY1RMAPK1AKT1 | |
| Hydrochloric Acid SCHEMBL30664702 | 0.83 | KMT2A (0.33) | TSHRLMNANPY1RMAPK1AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117222630-A | 2-acetamido-6-hydroxy-benzothiophene derivatives having antiviral activity | OTC制药公司(JSC) | 2023-12-12 | — | — | CN | disclosed |
| WO-2022173329-A1 | 2-ACETAMIDO-6-HYDROXY-BENZOTHIOPHENE DERIVATIVES WITH ANTIVIRAL ACTIVITY | Акционерное общество "Отисифарм" | 2022-08-18 | — | — | WO | disclosed |