Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.37 |
| ▸ | TSPO | P30536 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29800012 | 1.00 | PDK1 (0.37) | PDK1TSPOKMT2AMEN1L3MBTL1 | |
| SCHEMBL24682203 | 0.90 | MEN1 (0.39) | PDK1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL29800055 | 0.89 | TSPO (0.40) | TSPOKMT2AMEN1L3MBTL1NPC1 | |
| SCHEMBL24682198 | 0.89 | TSPO (0.40) | TSPOKMT2AMEN1L3MBTL1NPC1 | |
| SCHEMBL30701659 | 0.88 | KMT2A (0.34) | KMT2AMEN1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL24682972 | 0.88 | KMT2A (0.34) | KMT2AMEN1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL29799821 | 0.88 | HSP90AA1 (0.39) | TSPOKMT2AMEN1L3MBTL1NPC1 | |
| SCHEMBL24683203 | 0.88 | HSP90AA1 (0.39) | TSPOKMT2AMEN1L3MBTL1NPC1 | |
| SCHEMBL24682820 | 0.86 | KMT2A (0.35) | KMT2AMEN1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL24682207 | 0.86 | TSHR (0.38) | PDK1TSPOKMT2AMEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117222630-A | 2-acetamido-6-hydroxy-benzothiophene derivatives having antiviral activity | OTC制药公司(JSC) | 2023-12-12 | — | — | CN | disclosed |
| WO-2022173329-A1 | 2-ACETAMIDO-6-HYDROXY-BENZOTHIOPHENE DERIVATIVES WITH ANTIVIRAL ACTIVITY | Акционерное общество "Отисифарм" | 2022-08-18 | — | — | WO | disclosed |