Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | TSPO | P30536 | 2/20 | 0.32 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.32 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CRHBP | P24387 | 1/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.31 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30664682 | 0.88 | ALDH1A1 (0.35) | ALDH1A1TSHRKDM4EHPGDTSPO | |
| SCHEMBL24683892 | 0.88 | ALDH1A1 (0.35) | ALDH1A1TSHRKDM4EHPGDTSPO | |
| SCHEMBL24682963 | 0.87 | KMT2A (0.34) | ALDH1A1TSHRKDM4EHPGDGAA | |
| SCHEMBL24683206 | 0.86 | LMNA (0.38) | ALDH1A1KDM4EHPGDGAATSPO | |
| SCHEMBL24683840 | 0.86 | KDM4E (0.34) | ALDH1A1KDM4EHPGDGAATSPO | |
| SCHEMBL24682191 | 0.84 | NPSR1 (0.36) | ALDH1A1TSHRKDM4EHPGDGAA | |
| SCHEMBL24683871 | 0.84 | POLB (0.37) | ALDH1A1KDM4EHPGDGAATSPO | |
| SCHEMBL24683891 | 0.81 | TAAR1 (0.36) | ALDH1A1KDM4EHPGDGAAMAPT | |
| SCHEMBL29800145 | 0.81 | TAAR1 (0.36) | ALDH1A1KDM4EHPGDGAAMAPT | |
| SCHEMBL24682195 | 0.80 | LMNA (0.37) | ALDH1A1TSHRKDM4EHPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022173329-A1 | 2-ACETAMIDO-6-HYDROXY-BENZOTHIOPHENE DERIVATIVES WITH ANTIVIRAL ACTIVITY | Акционерное общество "Отисифарм" | 2022-08-18 | — | — | WO | disclosed |