Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 12/20 | 0.40 |
| ▸ | HSP90B1 | P14625 | 2/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HK1 | P19367 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24683888 | 1.00 | HSP90AA1 (0.40) | HSP90AA1HSP90B1HSP90AB1HSD17B10PKM | |
| SCHEMBL24683203 | 0.90 | HSP90AA1 (0.39) | HSP90AA1HSP90B1HSP90AB1PKMNPC1 | |
| SCHEMBL29799821 | 0.90 | HSP90AA1 (0.39) | HSP90AA1HSP90B1HSP90AB1PKMNPC1 | |
| SCHEMBL30664668 | 0.87 | HSP90AA1 (0.39) | HSP90AA1HSP90B1PKMNPC1RAB9A | |
| SCHEMBL24683224 | 0.87 | HSP90AA1 (0.39) | HSP90AA1HSP90B1PKMNPC1RAB9A | |
| SCHEMBL24683205 | 0.82 | LMNA (0.38) | HSP90AA1HSP90B1NPC1RAB9AMAPT | |
| SCHEMBL29799927 | 0.82 | LMNA (0.38) | HSP90AA1HSP90B1NPC1RAB9AMAPT | |
| SCHEMBL24683855 | 0.81 | HSP90AA1 (0.37) | HSP90AA1HSP90B1MAPTMEN1LMNA | |
| SCHEMBL30664726 | 0.81 | HSP90AA1 (0.37) | HSP90AA1HSP90B1MAPTMEN1LMNA | |
| SCHEMBL24682198 | 0.81 | TSPO (0.40) | NPC1RAB9AALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117222630-A | 2-acetamido-6-hydroxy-benzothiophene derivatives having antiviral activity | OTC制药公司(JSC) | 2023-12-12 | — | — | CN | disclosed |