Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | SHBG | P04278 | 1/20 | 0.31 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30701659 | 1.00 | KMT2A (0.34) | KMT2AMEN1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL24682820 | 0.90 | KMT2A (0.35) | KMT2AMEN1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL30701705 | 0.89 | MCL1 (0.39) | KMT2AMEN1HTTCASP3MCL1 | |
| SCHEMBL24683876 | 0.89 | MCL1 (0.39) | KMT2AMEN1HTTCASP3MCL1 | |
| SCHEMBL29799927 | 0.88 | LMNA (0.38) | KMT2AMEN1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL24683205 | 0.88 | LMNA (0.38) | KMT2AMEN1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL29800012 | 0.88 | PDK1 (0.37) | KMT2AMEN1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL24683226 | 0.88 | PDK1 (0.37) | KMT2AMEN1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL24682973 | 0.88 | MGLL (0.35) | KMT2AMEN1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL24683856 | 0.84 | ALOX5 (0.43) | KMT2AMEN1SMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117222630-A | 2-acetamido-6-hydroxy-benzothiophene derivatives having antiviral activity | OTC制药公司(JSC) | 2023-12-12 | — | — | CN | disclosed |
| WO-2022173329-A1 | 2-ACETAMIDO-6-HYDROXY-BENZOTHIOPHENE DERIVATIVES WITH ANTIVIRAL ACTIVITY | Акционерное общество "Отисифарм" | 2022-08-18 | — | — | WO | disclosed |