Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.43 |
| ▸ | CCR3 | P51677 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | RORC | P51449 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19330837 | 0.83 | OPRL1 (0.57) | KDM4EKMT2AOPRL1CCR3POLB | |
| SCHEMBL29087368 | 0.83 | SIGMAR1 (0.52) | KDM4EKMT2AOPRL1CCR3POLB | |
| SCHEMBL29087415 | 0.81 | CCR3 (0.61) | KDM4EKMT2AOPRL1CCR3POLB | |
| SCHEMBL19331018 | 0.80 | OPRL1 (0.47) | KDM4EKMT2AOPRL1CCR3POLB | |
| SCHEMBL15190515 | 0.76 | OPRL1 (0.47) | KMT2AOPRL1CCR3POLBCYP3A4 | |
| SCHEMBL19330960 | 0.76 | CHRM2 (0.47) | KDM4EKMT2AOPRL1CCR3POLB | |
| SCHEMBL3899225 | 0.75 | CYP2D6 (0.50) | KDM4EKMT2AOPRL1CCR3POLB | |
| SCHEMBL3908960 | 0.75 | OPRM1 (0.71) | OPRL1CCR3POLBOPRM1 | |
| SCHEMBL5193076 | 0.75 | OPRM1 (0.52) | KMT2AOPRL1CCR3POLBCYP3A4 | |
| SCHEMBL29087398 | 0.75 | RORC (0.41) | KDM4EKMT2ARORCSIGMAR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022167867-A1 | SUBSTITUTED CYCLIC MODULATORS OF PROTEIN PHOSPHATASE 2A (PP2A) AND METHODS USING SAME | RAPPTA THERAPEUTICS OY (FI) | 2022-08-11 | — | — | WO | disclosed |