Sulfuric Acid

Sulfuric Acid

SCHEMBL2468595

COc1cc2c(CCNC(C)=O)c[nH]c2cc1O.O=S(=O)(O)O

nearest known ligand 0.91

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 15/20 0.91
MTNR1B P49286 14/20 0.91
CYP1A2 P05177 6/20 0.91
CYP3A4 P08684 4/20 0.91
CYP2D6 P10635 4/20 0.91
KDM4E B2RXH2 3/20 0.91
HPGD P15428 3/20 0.91
HSD17B10 Q99714 2/20 0.91
NPSR1 Q6W5P4 2/20 0.91
APEX1 P27695 1/20 0.91
HTR2B P41595 3/20 0.70
MEN1 O00255 3/20 0.70
KMT2A Q03164 3/20 0.70
LMNA P02545 2/20 0.70
CYP2C19 P33261 2/20 0.70
CYP2C9 P11712 1/20 0.70
NFKB1 P19838 1/20 0.70
MAPK1 P28482 1/20 0.70
SLC6A4 P31645 1/20 0.70
THPO P40225 1/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29575897 0.95 MTNR1A (1.00) MTNR1AMTNR1BCYP1A2CYP3A4CYP2D6
SCHEMBL674970 0.95 MTNR1A (1.00) MTNR1AMTNR1BCYP1A2CYP3A4CYP2D6
SCHEMBL9189819 0.91 MTNR1A (0.91) MTNR1AMTNR1BCYP1A2CYP3A4CYP2D6
SCHEMBL31543696 0.91 MTNR1A (0.91) MTNR1AMTNR1BCYP1A2CYP3A4CYP2D6
SCHEMBL1773582 0.87 MTNR1A (1.00) MTNR1AMTNR1BCYP1A2CYP3A4CYP2D6
SCHEMBL342256 0.85 MTNR1A (0.82) MTNR1AMTNR1BCYP1A2CYP3A4CYP2D6
SCHEMBL342184 0.84 MTNR1A (0.79) MTNR1AMTNR1BCYP1A2CYP3A4CYP2D6
SCHEMBL8041780 0.83 MTNR1A (0.83) MTNR1AMTNR1BCYP1A2CYP3A4CYP2D6
SCHEMBL8053222 0.82 MTNR1A (0.81) MTNR1AMTNR1BCYP1A2CYP3A4CYP2D6
SCHEMBL1772618 0.82 HTR2B (1.00) MTNR1AMTNR1BCYP1A2CYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122072275-A Detection of biomarkers in biological samples 奥特森斯诊断有限公司 2026-05-22 CN claimed
US-20100120887-A1 SUSTAINED RELEASE FORMULATION OF MELATONIN THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2010-05-13 US claimed
CN-122072275-A Detection of biomarkers in biological samples 奥特森斯诊断有限公司 2026-05-22 CN disclosed
WO-2026104861-A1 IODBR1 AND DERIVATIVES THEREOF FOR TREATING SLEEP DISORDERS PHYTOQUEST LIMITED (GB) 2026-05-21 WO disclosed
US-20250107560-A1 CHRONOBIOLOGICAL FOOD FOR INFANTS AND METHOD FOR PRODUCING SAME PADITZ EKKEHART (DE) 2025-04-03 US disclosed
EP-4463011-A1 CHRONOBIOLOGICAL FOOD FOR INFANTS AND METHOD FOR PRODUCING SAME Paditz, Ekkehart (DE) 2024-11-20 EP disclosed
CN-116699003-B Circadian rhythm body fluid marker combination and UPLC-MS/MS detection method thereof 中国民用航空局民用航空医学中心 2023-12-26 CN disclosed
CN-116699003-A Circadian rhythm body fluid marker combination and UPLC-MS/MS detection method thereof 中国民用航空局民用航空医学中心 2023-09-05 CN disclosed
WO-2023135228-A1 CHRONOBIOLOGICAL FOOD FOR INFANTS AND METHOD FOR PRODUCING SAME PADITZ EKKEHART (DE) 2023-07-20 WO disclosed
WO-2023134856-A1 INFANT FOOD AND METHOD FOR PRODUCING SAME PADITZ EKKEHART (DE) 2023-07-20 WO disclosed
EP-4019017-A1 COMPOSITION COMPRISING MELATONIN, PIPERINE AND VITAMIN D, CONTROLLED-RELEASE FORMULATION AND USE THEREOF FOR THE TREATMENT OF SLEEP DISORDERS Uriach Consumer Healthcare, S.L. (ES) 2022-06-29 EP disclosed
US-20020068692-A1 Method for the treatment of neurological or neuropsychiatric disorders CLARENCEW PTY LTD. ORGANIZED UNDER THE LAW OF AUSTRIALIA (AU) 2002-06-06 US disclosed
EP-1189613-A1 METHOD FOR THE TREATMENT OF NEUROLOGICAL OR NEUROPSYCHIATRIC DISORDERS Clarencew Pty Ltd. (AU) 2002-03-27 EP disclosed
US-6310085-B1 SUBJECTING PATIENT WITH DISORDER ASSOCIATED WITH ALTERED DOPAMINE FUNCTION TO THERAPY WHICH BLOCKS AND/OR INHIBITS MELATONIN, PRECURSORS THEREOF AND/OR METABOLIC PRODUCTS THEREOF CLARENCEW PTY LTD. (AU) 2001-10-30 US disclosed
US-6235719-B1 CONTROLLING SLEEP CYCLE LABORATOIRE OENOBOL, S.A. (FR) 2001-05-22 US disclosed
WO-2000059504-A1 METHOD FOR THE TREATMENT OF NEUROLOGICAL OR NEUROPSYCHIATRIC DISORDERS CLARENCEW PTY LTD (AU) 2000-10-12 WO disclosed
EP-1032833-A2 USE OF OXIDATIVE STRESS DIAGNOSTIC PLOT AS A HEALTH INDICATOR Nikken Foods Co., Ltd. (JP) 2000-09-06 EP disclosed
EP-0964679-A1 METHOD FOR THE TREATMENT OF NEUROLOGICAL OR NEUROPSYCHIATRIC DISORDERS Clarencew Pty Ltd. (AU) 1999-12-22 EP disclosed
WO-1999063341-A2 USE OF OXIDATIVE STRESS DIAGNOSTIC PLOT AS A HEALTH INDICATOR FOR ASSESSING OXIDATIVE STRESS AND ITS CONTROL IN HUMANS NIKKEN FOODS CO., LTD. (JP) 1999-12-09 WO disclosed
WO-1998015267-A1 METHOD FOR THE TREATMENT OF NEUROLOGICAL OR NEUROPSYCHIATRIC DISORDERS CLARENCEW PTY LTD (AU) 1998-04-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020068692-A1 Method for the treatment of neurological or neuropsychiatric disorders COMT, HNMT, PNMT MTNR1A 7/4885MTNR1B 6/4885CYP1A2 387/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.