Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | CCR1 | P32246 | 2/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | RET | P07949 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3320854 | 0.87 | NAMPT (0.52) | NAMPTCYP3A4CYP2C9RAB9AMAPT | |
| SCHEMBL17208413 | 0.82 | NAMPT (0.47) | NAMPTRAB9AMAPTNPC1CCR1 | |
| SCHEMBL10291725 | 0.80 | POLB (0.62) | CYP2C9RAB9AMAPTNPC1CCR1 | |
| SCHEMBL15840481 | 0.79 | EPHX2 (0.48) | EPHX2 | |
| SCHEMBL10460507 | 0.79 | QDPR (0.62) | RAB9AMAPTNPC1CCR1PARP10 | |
| SCHEMBL28036178 | 0.78 | RAB9A (0.55) | RAB9AMAPTNPC1CCR1PARP10 | |
| SCHEMBL18805528 | 0.77 | NAMPT (0.60) | NAMPTMAPTSMN1; SMN2FAAH | |
| SCHEMBL2594236 | 0.77 | NAMPT (0.60) | NAMPTMAPTSMN1; SMN2FAAH | |
| SCHEMBL2636274 | 0.77 | RAB9A (0.57) | RAB9AMAPTNPC1CCR1PARP10 | |
| SCHEMBL31489002 | 0.76 | NAMPT (0.61) | NAMPTCYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022167867-A1 | SUBSTITUTED CYCLIC MODULATORS OF PROTEIN PHOSPHATASE 2A (PP2A) AND METHODS USING SAME | RAPPTA THERAPEUTICS OY (FI) | 2022-08-11 | — | — | WO | disclosed |