Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.44 |
| ▸ | PRKCG | P05129 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | FES | P07332 | 1/20 | 0.44 |
| ▸ | RET | P07949 | 1/20 | 0.44 |
| ▸ | ROS1 | P08922 | 1/20 | 0.44 |
| ▸ | FER | P16591 | 1/20 | 0.44 |
| ▸ | FLT1 | P17948 | 1/20 | 0.44 |
| ▸ | AXL | P30530 | 1/20 | 0.44 |
| ▸ | FLT4 | P35916 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.44 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.44 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24689881 | 0.91 | EGFR (0.51) | EPHX2NR1H4MAP4K4PRKCGROCK1 | |
| SCHEMBL24690119 | 0.87 | MAPT (0.46) | EGLN1GP6 | |
| SCHEMBL30019984 | 0.85 | CFD (0.45) | CFDEPHX2NR1H4JAK2MAP4K4 | |
| SCHEMBL24690091 | 0.84 | GP6 (0.51) | GP6 | |
| SCHEMBL24689873 | 0.82 | EPHX2 (0.51) | EPHX2NR1H4ROCK1EGFRHDAC3 | |
| SCHEMBL24690266 | 0.82 | EGLN1 (0.41) | EGLN1GP6HDAC3HDAC1 | |
| SCHEMBL24690114 | 0.80 | MAPT (0.43) | EGLN1 | |
| SCHEMBL24690116 | 0.78 | XDH (0.56) | EPHX2NR1H4XDH | |
| SCHEMBL24690118 | 0.77 | XDH (0.57) | SLKEGLN1GP6XDH | |
| SCHEMBL24690092 | 0.76 | ALDH1A1 (0.59) | GP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022224212-A1 | GPR35 AGONIST COMPOUNDS | HEPTARES THERAPEUTICS LIMITED (GB) | 2022-10-27 | — | — | WO | disclosed |