Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 4/20 | 0.43 |
| ▸ | LIPE | Q05469 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24690110 | 0.87 | L3MBTL1 (0.42) | LIPEMAPK1HPGDTHRBGABRA5 | |
| SCHEMBL8737477 | 0.83 | LIPE (0.56) | LIPEMAPK1MAPTLMNATHRB | |
| SCHEMBL24690108 | 0.80 | MRGPRX4 (0.47) | LIPEMAPTHPGDMAOBGABRA5 | |
| SCHEMBL13402167 | 0.79 | DRD2 (0.49) | MAPT | |
| SCHEMBL10175173 | 0.76 | EPHX2 (0.46) | — | |
| SCHEMBL2715216 | 0.75 | L3MBTL1 (0.56) | MAPK1MAPT | |
| SCHEMBL10274190 | 0.74 | HPGD (0.54) | LIPEMAPK1MAPTLMNAHPGD | |
| SCHEMBL15034210 | 0.74 | PTGDR2 (0.46) | MAOB | |
| SCHEMBL8463930 | 0.74 | KDM4E (0.51) | LIPEMAPK1MAPTLMNAHPGD | |
| SCHEMBL5077085 | 0.74 | HPGD (0.49) | LIPEMAPK1MAPTLMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022224212-A1 | GPR35 AGONIST COMPOUNDS | HEPTARES THERAPEUTICS LIMITED (GB) | 2022-10-27 | — | — | WO | disclosed |