Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.34 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18788152 | 0.84 | USP2 (0.57) | USP2TSHRALDH1A1PKMKDM4E | |
| SCHEMBL5457663 | 0.78 | NPC1 (0.52) | ALDH1A1KDM4EMAPTPOLB | |
| SCHEMBL18788145 | 0.76 | GRM2 (0.46) | TSHRALDH1A1KDM4EMAPTPOLB | |
| SCHEMBL23998512 | 0.73 | ADORA3 (0.51) | ALDH1A1 | |
| SCHEMBL20541989 | 0.70 | LMNA (0.38) | ALDH1A1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL17926551 | 0.66 | LMNA (0.40) | TSHRALDH1A1PKMKDM4EMAPT | |
| SCHEMBL18788176 | 0.65 | LMNA (0.44) | KDM4EMAPT | |
| SCHEMBL20449592 | 0.65 | KMT2A (0.36) | ALDH1A1PKMKDM4EPOLB | |
| SCHEMBL18788165 | 0.64 | LMNA (0.38) | — | |
| SCHEMBL31404515 | 0.64 | LMNA (0.38) | PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022256300-A1 | FUSED BICYCLIC HETEROCYCLIC COMPOUNDS AND USES THEREOF | Verge Analytics, Inc. (US) | 2022-12-08 | — | — | WO | disclosed |
| WO-2022256300-A1 | FUSED BICYCLIC HETEROCYCLIC COMPOUNDS AND USES THEREOF | Verge Analytics, Inc. (US) | 2022-12-08 | — | — | WO | disclosed |