Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAVCR2 | Q8TDQ0 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
| ▸ | TYMP | P19971 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2041629 | 0.67 | — | — | |
| SCHEMBL24693472 | 0.61 | USP2 (0.40) | HAVCR2ALDH1A1USP2TSHR | |
| SCHEMBL17926568 | 0.59 | XDH (0.39) | ALDH1A1LMNAHPGDTSHR | |
| SCHEMBL14194705 | 0.59 | PLAT (0.44) | TSHR | |
| SCHEMBL18788132 | 0.57 | LPO (0.33) | ALDH1A1HPGD | |
| SCHEMBL22958307 | 0.55 | ALDH1A1 (0.50) | ALDH1A1LMNAHPGDAPOBEC3G | |
| SCHEMBL2632907 | 0.48 | — | — | |
| SCHEMBL14926166 | 0.48 | PDE10A (0.37) | ALDH1A1LMNA | |
| SCHEMBL11859252 | 0.47 | POLB (0.31) | — | |
| SCHEMBL25214869 | 0.46 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022256300-A1 | FUSED BICYCLIC HETEROCYCLIC COMPOUNDS AND USES THEREOF | Verge Analytics, Inc. (US) | 2022-12-08 | — | — | WO | disclosed |
| WO-2022256300-A1 | FUSED BICYCLIC HETEROCYCLIC COMPOUNDS AND USES THEREOF | Verge Analytics, Inc. (US) | 2022-12-08 | — | — | WO | disclosed |