Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KHK | P50053 | 1/20 | 0.38 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24696458 | 0.81 | TSHR (0.35) | — | |
| SCHEMBL7950341 | 0.77 | KEAP1 (0.42) | KHKTRPV4 | |
| SCHEMBL8167910 | 0.76 | KDM4E (0.44) | — | |
| SCHEMBL13660126 | 0.75 | KHK (0.48) | KHKTRPV4ADRB2ADRB1 | |
| SCHEMBL6661759 | 0.73 | KHK (0.47) | KHKTRPV4ADRB2ADRB1 | |
| SCHEMBL332547 | 0.73 | TRPV4 (0.56) | KHKTRPV4ADRB2ADRB1 | |
| SCHEMBL31127856 | 0.73 | POLB (0.35) | — | |
| SCHEMBL31550240 | 0.73 | TRPV4 (0.42) | KHKTRPV4ADRB2ADRB1AR | |
| SCHEMBL27351641 | 0.72 | KDM4E (0.35) | KHKTRPV4ADRB2ADRB1AR | |
| SCHEMBL5846599 | 0.72 | KHK (0.43) | KHKTRPV4ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022254027-A1 | 3-PYRROLYLSULFONAMIDE COMPOUNDS AS GPR17 ANTAGONISTS | REWIND THERAPEUTICS NV (BE) | 2022-12-08 | — | — | WO | disclosed |