Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | KHK | P50053 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8167910 | 0.80 | KDM4E (0.44) | KDM4EHSD17B10KMT2ARXFP1POLB | |
| SCHEMBL19554362 | 0.79 | KEAP1 (0.46) | KEAP1NOTUMKDM4EHSD17B10KMT2A | |
| SCHEMBL16411017 | 0.79 | KEAP1 (0.46) | KEAP1NOTUMKDM4EHSD17B10KMT2A | |
| SCHEMBL16968396 | 0.78 | KDM4E (0.50) | NOTUMKDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL24697183 | 0.77 | KHK (0.38) | KHKTRPV4 | |
| SCHEMBL604580 | 0.77 | KEAP1 (0.50) | KEAP1KDM4EHSD17B10KMT2AGFER | |
| SCHEMBL30222084 | 0.77 | KEAP1 (0.50) | KEAP1KDM4EHSD17B10KMT2AGFER | |
| SCHEMBL13660126 | 0.76 | KHK (0.48) | KHKKDM4EKMT2ATRPV4MEN1 | |
| SCHEMBL8300964 | 0.76 | TRPV4 (0.48) | KEAP1NOTUMKDM4EHSD17B10TRPV4 | |
| SCHEMBL11116363 | 0.74 | KDM4E (0.47) | NOTUMKDM4EHSD17B10ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6175010-B1 | 3-amino-1-cyanophenyl-uracils | BAYER AKTIENGESELLSCHAFT (DE) | 2001-01-16 | — | — | US | disclosed |