Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR5A | P47898 | 2/20 | 0.31 |
| ▸ | MMP12 | P39900 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18322187 | 0.82 | HTR5A (0.32) | HTR5AMMP12 | |
| SCHEMBL12301085 | 0.78 | KDM4E (0.36) | HTR5AMMP12 | |
| SCHEMBL17208907 | 0.75 | ADRA2A (0.35) | HTR5AMMP12 | |
| SCHEMBL14493442 | 0.73 | HTR5A (0.34) | HTR5A | |
| SCHEMBL22549228 | 0.71 | HTR5A (0.33) | HTR5A | |
| SCHEMBL12233255 | 0.69 | KDM4E (0.35) | HTR5AMMP12 | |
| SCHEMBL18322121 | 0.69 | MMP12 (0.35) | HTR5AMMP12 | |
| SCHEMBL22131607 | 0.68 | ALDH1A1 (0.50) | — | |
| SCHEMBL18322106 | 0.68 | AKR1B1 (0.38) | — | |
| Hydrochloric Acid SCHEMBL20297351 | 0.68 | MMP12 (0.34) | HTR5AMMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022212194-A1 | KHK INHIBITORS | GILEAD SCIENCES, INC. (US) | 2022-10-06 | — | — | WO | disclosed |