Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 4/20 | 0.34 |
| ▸ | VCP | P55072 | 5/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30015382 | 1.00 | PDK1 (0.39) | PDK1PDK2PDK3PDK4GFER | |
| SCHEMBL30015877 | 0.88 | PDK1 (0.40) | PDK1PDK2PDK3PDK4GFER | |
| SCHEMBL30016341 | 0.88 | MTOR (0.44) | PDK1PDK2PDK3PDK4GFER | |
| SCHEMBL24699474 | 0.88 | MTOR (0.44) | PDK1PDK2PDK3PDK4GFER | |
| SCHEMBL24699461 | 0.88 | PDK1 (0.40) | PDK1PDK2PDK3PDK4GFER | |
| SCHEMBL24699484 | 0.86 | PDE7A (0.41) | PDK1PDK2PDK3PDK4ALDH1A1 | |
| SCHEMBL30015689 | 0.86 | PDE7A (0.41) | PDK1PDK2PDK3PDK4ALDH1A1 | |
| SCHEMBL24698594 | 0.86 | MEN1 (0.39) | PDK1PDK2PDK3PDK4ALDH1A1 | |
| SCHEMBL29134886 | 0.86 | MEN1 (0.39) | PDK1PDK2PDK3PDK4ALDH1A1 | |
| SCHEMBL30015817 | 0.86 | MEN1 (0.39) | PDK1PDK2PDK3PDK4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022212194-A1 | KHK INHIBITORS | GILEAD SCIENCES, INC. (US) | 2022-10-06 | — | — | WO | disclosed |