Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 2/20 | 0.30 |
| ▸ | CCND1 | P24385 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21475616 | 0.92 | PLG (0.36) | PLGPLAUCDK4CCND1 | |
| SCHEMBL24699674 | 0.89 | PLG (0.36) | PLGPLAUCDK4CCND1 | |
| SCHEMBL21473895 | 0.87 | CDK4 (0.32) | PLGPLAUCDK4CCND1 | |
| SCHEMBL21473896 | 0.87 | CDK4 (0.34) | PLGPLAUCDK4CCND1 | |
| SCHEMBL21475601 | 0.85 | CRHR1 (0.32) | PLGPLAU | |
| SCHEMBL16639341 | 0.85 | CASP3 (0.30) | CDK4CCND1 | |
| SCHEMBL29636227 | 0.85 | CASP3 (0.30) | CDK4CCND1 | |
| SCHEMBL21475597 | 0.84 | PLG (0.33) | PLGPLAUCDK4CCND1 | |
| SCHEMBL21473903 | 0.83 | GPR88 (0.34) | — | |
| SCHEMBL16639330 | 0.83 | RXRA (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11512039-B2 | Aromatic amine derivatives, preparation methods therefor, and uses thereof | GUANGZHOU CHINARAY OPTOELECTRONIC MATERIALS LTD. (CN) | 2022-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11512039-B2 | Aromatic amine derivatives, preparation methods therefor, and uses thereof | SLC7A1, WEE1, SLC7A5 | PLG 3503/4885PLAU 3740/4885CDK4 2113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.