Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GLP1R | P43220 | 8/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26167786 | 0.94 | HPGD (0.43) | HPGDLMNAPKMTSHRMEN1 | |
| SCHEMBL24253180 | 0.92 | TSHR (0.43) | HPGDLMNAPKMTSHRMEN1 | |
| SCHEMBL17123136 | 0.91 | ALDH1A1 (0.44) | HPGDLMNAPKMTSHRMEN1 | |
| SCHEMBL27312098 | 0.89 | MEN1 (0.45) | HPGDLMNAPKMTSHRMEN1 | |
| SCHEMBL25128191 | 0.89 | MEN1 (0.45) | HPGDLMNAPKMTSHRMEN1 | |
| SCHEMBL27312182 | 0.89 | MEN1 (0.45) | HPGDLMNAPKMTSHRMEN1 | |
| SCHEMBL27312181 | 0.89 | MEN1 (0.45) | HPGDLMNAPKMTSHRMEN1 | |
| SCHEMBL26866027 | 0.88 | GLP1R (0.41) | HPGDLMNAPKMTSHRMEN1 | |
| SCHEMBL18707765 | 0.87 | HPGD (0.49) | HPGDLMNAPKMTSHRMEN1 | |
| SCHEMBL26412077 | 0.87 | MEN1 (0.47) | HPGDTSHRMEN1KMT2ACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230158169-A1 | LINKERS FOR IMPROVING THE STABILITY OF BIOCONJUGATES AND THE SELECTIVITY OF PAYLOAD RELEASE | AUDAX PRIVATE DEBT LLC, AS AGENT | 2023-05-25 | — | — | US | disclosed |
| US-11510994-B2 | Linkers for improving the stability of bioconjugates and the selectivity of payload release | EqIP, LLC (US) | 2022-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11510994-B2 | Linkers for improving the stability of bioconjugates and the selectivity of payload release | CTSA, CTSS, CTSV | HPGD 4459/4885LMNA 659/4885PKM 4052/4885 |
| US-20230158169-A1 | LINKERS FOR IMPROVING THE STABILITY OF BIOCONJUGATES AND THE SELECTIVITY OF PAYLOAD RELEASE | CTSA, CTSS, CTSV | HPGD 4459/4885LMNA 659/4885PKM 4052/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.