Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GLP1R | P43220 | 8/20 | 0.34 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA4 | P22748 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27312181 | 0.98 | MEN1 (0.45) | ALDH1A1MEN1KMT2AHPGDLMNA | |
| SCHEMBL27312098 | 0.98 | MEN1 (0.45) | ALDH1A1MEN1KMT2AHPGDLMNA | |
| SCHEMBL25128191 | 0.98 | MEN1 (0.45) | ALDH1A1MEN1KMT2AHPGDLMNA | |
| SCHEMBL27312182 | 0.98 | MEN1 (0.45) | ALDH1A1MEN1KMT2AHPGDLMNA | |
| SCHEMBL25533100 | 0.91 | HPGD (0.45) | ALDH1A1MEN1KMT2AHPGDLMNA | |
| SCHEMBL24700121 | 0.91 | HPGD (0.45) | ALDH1A1MEN1KMT2AHPGDLMNA | |
| SCHEMBL26412077 | 0.90 | MEN1 (0.47) | ALDH1A1MEN1KMT2AHPGDCNR1 | |
| SCHEMBL23386933 | 0.88 | MEN1 (0.50) | ALDH1A1MEN1KMT2AHPGDTSHR | |
| SCHEMBL25812337 | 0.88 | MEN1 (0.46) | ALDH1A1MEN1KMT2AHPGDCNR1 | |
| SCHEMBL13616087 | 0.88 | MEN1 (0.53) | ALDH1A1MEN1KMT2AHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11510994-B2 | Linkers for improving the stability of bioconjugates and the selectivity of payload release | EqIP, LLC (US) | 2022-11-29 | — | — | US | disclosed |
| US-9745303-B2 | Synthesis and intermediates of pyrrolobenzodiazepine derivatives for conjugation | MEDIMMUNE LIMITED (GB) | 2017-08-29 | — | — | US | disclosed |
| US-20150274737-A1 | SYNTHESIS AND INTERMEDIATES OF PYRROLOBENZODIAZEPINE DERIVATIVES FOR CONJUGATION | MEDIMMUNE LIMITED (GB) | 2015-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11510994-B2 | Linkers for improving the stability of bioconjugates and the selectivity of payload release | CTSA, CTSS, CTSV | ALDH1A1 3509/4885MEN1 3517/4885KMT2A 3207/4885 |
| US-20150274737-A1 | SYNTHESIS AND INTERMEDIATES OF PYRROLOBENZODIAZEPINE DERIVATIVES FOR CONJUGATION | CYP2C19, GABRE, CYP3A7 | ALDH1A1 927/4885MEN1 1943/4885KMT2A 1347/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.