Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.43 |
| ▸ | ASAH1 | Q13510 | 3/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL23123885 | 0.99 | OPRD1 (0.45) | NAMPTOPRD1OPRM1ASAH1EPHX2 | |
| Hydrochloric Acid SCHEMBL29795146 | 0.90 | KEAP1 (0.41) | NAMPTOPRD1OPRM1ASAH1EPHX2 | |
| SCHEMBL23124056 | 0.81 | EPHX2 (0.52) | NAMPTASAH1EPHX2SIGMAR1FKBP1A | |
| SCHEMBL23124249 | 0.79 | FKBP1A (0.48) | NAMPTASAH1EPHX2FKBP1A | |
| SCHEMBL24700666 | 0.78 | ASAH1 (0.51) | NAMPTASAH1EPHX2FKBP1A | |
| SCHEMBL23123655 | 0.78 | OPRM1 (0.51) | NAMPTOPRD1OPRM1ASAH1EPHX2 | |
| Hydrochloric Acid SCHEMBL23123245 | 0.78 | ASAH1 (0.50) | NAMPTASAH1EPHX2FKBP1A | |
| SCHEMBL23123649 | 0.77 | NAMPT (0.45) | NAMPTOPRM1ASAH1EPHX2OPRL1 | |
| SCHEMBL23124126 | 0.77 | EPHX2 (0.47) | NAMPTASAH1EPHX2SIGMAR1 | |
| SCHEMBL24700279 | 0.74 | NAMPT (0.54) | NAMPTASAH1EPHX2FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220380314-A1 | SUBSTITUTED, SATURATED AND UNSATURATED N-HETEROCYCLIC CARBOXAMIDES AND RELATED COMPOUNDS FOR THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS | BIAL R&D INVEST S A (PT) | 2022-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220380314-A1 | SUBSTITUTED, SATURATED AND UNSATURATED N-HETEROCYCLIC CARBOXAMIDES AND RELATED COMPOUNDS FOR THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS | GBA1, GBA2, CLN6 | NAMPT 92/4885OPRD1 1327/4885OPRM1 1690/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.