Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 1/20 | 0.42 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.41 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.41 |
| ▸ | GSPT1 | P15170 | 1/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | LIPE | Q05469 | 4/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4433353 | 0.83 | ALDH1A1 (0.52) | ALPLSLC22A12SLC40A1MCHR1ADRA2A | |
| SCHEMBL1723245 | 0.80 | MCHR1 (0.47) | ALPLSLC22A12SLC40A1MCHR1ADRA2A | |
| SCHEMBL23052300 | 0.79 | DRD2 (0.52) | DRD2ADRA1DADRA1AADRA1B | |
| SCHEMBL27999788 | 0.72 | ALPL (0.53) | ALPLSLC22A12SLC40A1GSPT1DDB1 | |
| SCHEMBL10154346 | 0.70 | ALPL (0.52) | ALPLSLC22A12SLC40A1MAPTBRD4 | |
| SCHEMBL8229520 | 0.70 | ALPL (0.52) | ALPLSLC22A12SLC40A1MAPTBRD4 | |
| SCHEMBL418590 | 0.70 | ALPL (0.52) | ALPLSLC22A12SLC40A1GSPT1DDB1 | |
| SCHEMBL28312855 | 0.70 | SLC22A12 (0.54) | ALPLSLC22A12SLC40A1GSPT1DDB1 | |
| SCHEMBL6735794 | 0.69 | ALPL (0.51) | ALPLSLC22A12SLC40A1GSPT1DDB1 | |
| SCHEMBL3006664 | 0.68 | MCHR1 (0.66) | ALPLMCHR1ADRA2ANPY5RL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2371366-A1 | Heterocyclo inhibitors of potassium channel function | Bristol-Myers Squibb Company (US) | 2011-10-05 | — | — | EP | disclosed |