Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 2/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26782822 | 0.82 | CTSK (0.40) | HSD11B1NFKB1NFKB2RELAKDM1A | |
| SCHEMBL19931880 | 0.81 | HSD11B1 (0.36) | HSD11B1NFKB1NFKB2RELAKDM1A | |
| SCHEMBL23900570 | 0.80 | HSD11B1 (0.37) | HSD11B1NFKB1NFKB2RELAKDM1A | |
| SCHEMBL1844173 | 0.80 | HSD11B1 (0.58) | HSD11B1HSD11B2MEN1MAPK1KMT2A | |
| SCHEMBL1844175 | 0.80 | HSD11B1 (0.58) | HSD11B1HSD11B2MEN1MAPK1KMT2A | |
| SCHEMBL1844176 | 0.80 | HSD11B1 (0.58) | HSD11B1HSD11B2MEN1MAPK1KMT2A | |
| SCHEMBL23281289 | 0.78 | NFKB1 (0.40) | HSD11B1NFKB1NFKB2RELAKDM1A | |
| SCHEMBL23625485 | 0.76 | BTK (0.44) | HSD11B1NFKB1NFKB2RELAKDM1A | |
| SCHEMBL24543130 | 0.76 | BTK (0.44) | HSD11B1NFKB1NFKB2RELAKDM1A | |
| SCHEMBL23562417 | 0.76 | HSD11B1 (0.47) | HSD11B1NFKB1NFKB2RELAKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022254377-A1 | NEODEGRADER-ANTI-CD33 ANTIBODY CONJUGATES | ORUM THERAPEUTICS, INC. (KR) | 2022-12-08 | — | — | WO | disclosed |