Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 2/20 | 0.59 |
| ▸ | CNR1 | P21554 | 2/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | FAAH | O00519 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | APEX1 | P27695 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | GPR18 | Q14330 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL517480 | 0.85 | TOP1 (0.63) | TOP1CNR1HRH3USP2POLB | |
| SCHEMBL10991674 | 0.84 | HSP90AA1 (0.64) | MEN1FAAHALDH1A1ALOX15KMT2A | |
| SCHEMBL18173794 | 0.84 | HSP90AA1 (0.64) | MEN1FAAHALDH1A1ALOX15KMT2A | |
| SCHEMBL18151866 | 0.84 | HSP90AA1 (0.64) | MEN1FAAHALDH1A1ALOX15KMT2A | |
| SCHEMBL11000599 | 0.84 | HSP90AA1 (0.64) | MEN1FAAHALDH1A1ALOX15KMT2A | |
| SCHEMBL19227172 | 0.84 | HSP90AA1 (0.64) | MEN1FAAHALDH1A1ALOX15KMT2A | |
| SCHEMBL23193125 | 0.83 | TOP1 (0.61) | TOP1CNR1HRH3KDM4EMEN1 | |
| SCHEMBL10999545 | 0.82 | — | — | |
| SCHEMBL3485558 | 0.81 | CNR1 (0.78) | CNR1MEN1FAAHALDH1A1MAPT | |
| SCHEMBL422846 | 0.81 | TERT (0.66) | TOP1HRH3MEN1FAAHUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11524933-B2 | In or relating to organic compounds | GIVAUDAN SA (CH) | 2022-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11524933-B2 | In or relating to organic compounds | GABRB3, GABRB1, GABRB2 | TOP1 4709/4885CNR1 173/4885HRH3 320/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.